Certainly if the invading aliens decided to land on Earth while humans were still living, occupy and enslave humans we could wage a guerrilla war and have some chance of driving them off with a war of attrition.
I do not believe that a interstellar race with designs on Earth would have any use for human slaves. I there for reason that they would not bother to make a “beach landing” on Earth and take Earth by brute force.
A more reasoned approach for a race of vastly superior technology is to use a self replicating bioengineered virus designed to kill humans, mentally incapacitate or if they are willing to wait a few years render humans sterile.
Why should they challenge us physically when they can introduce a bio-organism that will do the work for them much more cheaply and with out risk to them physically. They kidnap a few hosts, infect them and return them to Earth. The hosts introduce the virus to the general population. The virus spreads rapidly and wipes out the vast majority of the population (if not all). Any remaining population could be exterminated by hunter/killer robots.
In my opinion we would never lay eyes on the invaders. To the invaders it would be an unnecessary risk.