The ump called the strike and then immediately pointed toward first, and then called the strike again. He apparently also said something because pierzynski started to head across the plate and then immediately spun around and ran toward first. Unfortunately for the Angels the catcher had already exited stage right.
On the replay the ball clearly bounces before entering the webbing of the mitt. However there is no telltale puff of dirt leading me to assume he got the mitt under it.
And following your example, Pierzynski played completely through the play.
The ump rung him up. The play is dead. The inning is over. Period.