Posted on 09/09/2021 6:58:17 AM PDT by numberonepal
Niacin and Melatonin work in synergy. The melatonin opens the gateway to cells and the inflammation within the cells. Niacin gets inside and kicks the crap out of it. We are all depleted of melatonin, so everyone's doses are different.
The Sweet Spot is when there is No Flush. Not even a tingle occurs. Hence, all the melatonin is being used up as well as the niacin to remove inflammation and restore the cells to homeostasis. The Flush is when excess niacin is not being used by the melatonin and goes to the skin capillaries.
The environmental stresses of modern life can lead to shortages of nutrients, especially melatonin and niacin, leading to the accumulation of free radicals and inflammation. The virus was targeted to affect the ACE2 receptors, which are regulated by melatonin and niacin. Once in your cells the virus consumes your energy, depletes melatonin, down-regulates the ACE2 receptors (especially in the intestines producing a leaky gut) giving the virus and spikes easy access to your brain and nervous system through the Vagus nerve.
The virus thrives in a melatonin/niacin deficient environment. The virus uses the energy from inflammation for its fitness (fuel). Supplementing melatonin and niacin reduces the inflammation that makes your body more vulnerable and reactivates your immune system to take care of the virus.
Over the course of life the lack of nutrients, especially melatonin and niacin, can't counter the progression of bad health behaviors throughout that life. New exposures like electronics, geothermal shifts, etc, a stressful life and poorer quality food these days all compound these deficiencies. Our continued dynamic deficiency in especially NIATONIN (niacin/melatonin) leads to the accumulation of more energy not expended out as per in. Because of this free radical electrons form and inflammation accumulates.
It's literally like the virus and covid pathogenesis, just slower.
These viruses or their gain of function research - whatever you want to imagine it is - have evolved since SARS-1 in 2000 to target these energy receptors; aka ACE2; what niacin and melatonin regulate.
It's a feasting ground for them (viruses).
Note:
Niacin and melatonin regulate ACE2 (Angiotensin-converting enzyme 2).
ACE2 is an enzyme attached to the membrane of cells located in the intestines, kidney, testis, gallbladder, and heart. ACE2 lowers blood pressure by catalyzing the hydrolysis of angiotensin II into angiotensin.
They're (viruses) thermodynamically attracted to people who have more inflammation for them to use for their fitness (fuel). These high expressed ACE2 (aka niacin receptors) along with the SR-B1 coreceptor right next to it - they (virus) sneak in this.
Note:
SR-B1 is a scavenger receptor class B type 1. It functions as a receptor for high-density lipoprotein. It is also know as CD36, a scavenger receptor class B member 3.
SR-BI/CD36 chimeric receptors define extracellular subdomains of SR-BI critical for cholesterol transport
https://pubmed.ncbi.nlm.nih.gov/25211142/
The SR-B1 is where HDL dumps off cholesterol from blood into tissue to prevent atherosclerosis. Because the cholesterol was leaking out of the tissue after it reached threshold, it can not contain it anymore due to too much pressure. As a result, HDL lowers because it's not getting developed in the liver anymore. The HDL has to attend to scooping more cholesterol back into tissue, and is used up real quick.
The virus then gets in cells and as it literally continues to consume your energy until it reaches a threshold it needs of energy to double (replicate). As it does this it depletes melatonin. It also makes it a lot easier if you have deficient melatonin. You can see now why unhealthy and older people who have not had enough melatonin and niacin as most at risk. They also have low HDL/high TG (triglycerides). The depleted melatonin makes the PDC receptor, already stunted from accumulated inflammation over a lifetime, from pyruvate to Acetyl-CoA even more stunted. Due to this melatonin gets gradually even more depleted into say long haul COVID. As soon as the virus meets threshold to replicate it moves out the mitochondria, and on to the next one (cell) like a bad ex-girlfriend. Repeat forward. This is why COVID long haulers flush like crazy with even 50 mg doses of niacin.
Note:
• Type I interferons (IFNs) derived from plasmacytoid dendritic cells (PDCs) are critical for antiviral responses
• Pyruvic acid or pyruvate is a key intermediate in the glycolytic and pyruvate dehydrogenase pathways, which are involved in biological energy production.
• Acetyl-CoA is a molecule that participates in many biochemical reactions in protein, carbohydrate and lipid metabolism.
As the virus leaves each cell, it and all the crazy inflammation it amplified [hypered], leaves melatonin depleted and stunts further the PDC from pyruvate to acetylCoA. This is needed for AAANAT receptor from tryptophan to serotonin to melatonin stunted too, and so melatonin isn't made more and more.
Note:
The key regulatory step in melatonin synthesis is catalyzed by arylalkylamine N-acetyltransferase (AANAT), which converts serotonin to N-acetylserotonin.
This leaves ACE2 downregulated, and happens especially in the intestines/colon.
This is how the virus/spikes - like IVM gains easy access to your brain/nervous system then - your gut becomes leaky with this ravaging of melatonin and inflammation. This gives easy access through the Vagus nerve to cross into BBB (blood brain barrier) and nervous systems where the most bang for the buck energy is for them.
Basically the virus/spikes have to deplete your already deficient melatonin and niacin to succeed and be thermodynamically attracted in the first place.
So keeping NIATONIN sufficient/repleting it takes back control of YOUR energy metabolism that the spikes try to take over for their food (energy).
It (NIATONIN) doesn't just push out inflammation. It allows T-cell differentiation (melatonin through ACE2 aka GPR109A expression). Then niacin comes in which is literally an innate/mandatory function of the recruitment and facilitation of T-cells, killer cells, and B cells. It induces phagocytosis, denatures, kills, and clears the virus as well as all pathogens and all toxins. It's a feasting grounds for them.
Note:
GPR109A (encoded by Niacr1) is a receptor for butyrate in the colon. GPR109A is also a receptor for niacin, which is also produced by gut microbiota and suppresses intestinal inflammation.
https://pubmed.ncbi.nlm.nih.gov/24412617/
NIACIN: https://purebulk.com/products/niacin-vitamin-b3-immediate-release?sca_ref=1004090.8JspdBHd04…
MELATONIN: https://purebulk.com/products/melatonin?sca_ref=1004090.8JspdBHd04…
Precision (0.000 g) Scale: https://purebulk.com/products/gemini-20-digital-scale?sca_ref=1004090.8JspdBHd04…
This graphic contains the protocol. Please read it all, especially the top portion where is says to eliminate certain things while using the protocol.
Latest version of the protocol includes niacin, creatine, trimethylglycine, other B vitamins, grass-fed beef liver (especially for Vitamin A), and lipoic acid. See the website for details: http://hom3ostasis.com.
Bkmk
BKMk
ThankQ, AZLiberty. I wish he would just spell homeostasis the normal way. What’s up with that? That’s why I couldn’t find him. ;)
I pronounce it home-three-oh-stasis.
Dmitry is unafraid to stand up for what he believes in. In this video he goes to some huge medical institution (NIH?) on a Sunday to drop off information about his research with somebody there. He has a 15-minutes conversation with the security folks, educating them on the importance of his niacin work.
https://t.me/HOM3OSTASIS/331701
Interesting changes in the niatonin world. Dmitry’s still trying to figure out how melatonin fits into the mix, but meanwhile he has simplified his introductory protocol to just two ingredients. One is flush niacin, of course: 1-2 g. The other is new: vitamin E, in its most natural d-alpha tocopherol form (not ester/acetate/succinate): 500-1000 mg.
Then there’s this: https://nyulangone.org/news/schizophrenia-second-only-age-greatest-risk-factor-covid-19-death. Since schizophrenia is such a risk factor, “they” are now advocating that victims get additional vaccine attention — like that will help them. Much schizophrenia is due to niacin deficiency. How about we give them niacin, thus protecting them from COVID at the same time?
You wouldn’t want to HEAL anybody now would you?
What’s up with the Dmitry Tele channel? Looks to be gone.
I haven’t been paying close enough attention to know the details, but I think that Dmitry closed down the Hom3ostasis Telegram channel in favor of the paid web site. The Hom3ostasisTestimonials channel is now called T3stimonials.
The latest revision of the niacin protocol (from Dmitry’s Platinum member presentation today) is niacin, d-alpha tocopherol (natural Vitamin E), selenium yeast, and folic acid.
This is interesting (from http://www.doctoryourself.com/niacinreviews.html):
“There is a chemical found in quantity in the bodies of schizophrenic persons. It is an indole called adrenochrome. Adrenochrome (which is oxidized adrenalin) has an almost LSD-like effect on the body. That might well explain their behavior. Niacin serves to reduce the body’s production of this toxic material.”
That website belongs to Dr. Andrew Saul, who was co-author with Dr. Abraham Hoffer of “Niacin: The Real Story”. Hoffer was the one who discovered that niacin beats schizophrenia.
I just posted, but only to myself.
Recently got an article from the Dr. Ardis crowd. They’re now pushing nicotine (not nicotinic acid) as a treatment for vaxx injury. Also fasting, hyperbaric oxygen, and “urotherapy” (drinking, injecting, or having an enema with one’s own urine). They claim that urine contains stem cells, which can help repair cells damaged by mRNA bioweapons.
Dmitry thinks fasting is a dumb idea. The body needs nutrition to heal, so why deny it. The main point of the intermittent fasting fad is to provide the body with a brief respite from inflammation. Niacin reduces inflammation 24/7.
That said, the body sometimes manifests miracle cures during long-duration fasting. Some parasites, I suspect, may just get up and leave due to the change in their environment.
Candida comes to mind.
Dmitry’s done it again. A week ago he was completely certain that niacin + ferrolectin was the way to go, and now he’s completely certain that niacin + L-glutamine is the one true combination.
At least the niacin part is consistent.
I love that he keeps investigating and experimenting. I feel like I’m on a high-wire, however, when I try to communicate the niacin protocol to other people and expect them to follow it even though it changes before they get their Amazon delivery.
By the way, Amazon doesn’t take returns on supplements, even unopened.
That’s the test of a true scientist.
I’ve been taking some business training from the Grant Cardone organization — great stuff. One of their businesses is http://10XHealthSystem.com, which is at the opposite end of the spectrum from the one-size-fits-all niacin regiment. They analyze your DNA to find out which nutrients your body has trouble metabolizing and which amino acids your body doesn’t make enough of (or makes too much of). And they analyze your blood to see what else you might be missing. Then they recommend supplements and other non-medical interventions to bring you up to amazing health.
I’ve already had a cheek swab for my DNA here at the conference in Las Vegas and I’ll give them a blood sample when I get back to Arizona. I’ll be interested to know if they can tell that I’ve been on niacin.
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