>How does the whole NIATONIN thing work?

Telegram and FR | September 9, 2021 | Dr. Dmitry Kats (interpreted)

[numberonepal]

How does the whole NIATONIN thing work?

LAYMAN'S VERSION

Niacin and Melatonin work in synergy. The melatonin opens the gateway to cells and the inflammation within the cells. Niacin gets inside and kicks the crap out of it. We are all depleted of melatonin, so everyone's doses are different.

The Sweet Spot is when there is No Flush. Not even a tingle occurs. Hence, all the melatonin is being used up as well as the niacin to remove inflammation and restore the cells to homeostasis. The Flush is when excess niacin is not being used by the melatonin and goes to the skin capillaries.

The environmental stresses of modern life can lead to shortages of nutrients, especially melatonin and niacin, leading to the accumulation of free radicals and inflammation. The virus was targeted to affect the ACE2 receptors, which are regulated by melatonin and niacin. Once in your cells the virus consumes your energy, depletes melatonin, down-regulates the ACE2 receptors (especially in the intestines producing a leaky gut) giving the virus and spikes easy access to your brain and nervous system through the Vagus nerve.

The virus thrives in a melatonin/niacin deficient environment. The virus uses the energy from inflammation for its fitness (fuel). Supplementing melatonin and niacin reduces the inflammation that makes your body more vulnerable and reactivates your immune system to take care of the virus.

THE DR KATS LAYMAN'S VERSION
(edited for clarity - English is not his first language)

Over the course of life the lack of nutrients, especially melatonin and niacin, can't counter the progression of bad health behaviors throughout that life. New exposures like electronics, geothermal shifts, etc, a stressful life and poorer quality food these days all compound these deficiencies. Our continued dynamic deficiency in especially NIATONIN (niacin/melatonin) leads to the accumulation of more energy not expended out as per in. Because of this free radical electrons form and inflammation accumulates.

It's literally like the virus and covid pathogenesis, just slower.

These viruses or their gain of function research - whatever you want to imagine it is - have evolved since SARS-1 in 2000 to target these energy receptors; aka ACE2; what niacin and melatonin regulate.

It's a feasting ground for them (viruses).

Note:
Niacin and melatonin regulate ACE2 (Angiotensin-converting enzyme 2).
ACE2 is an enzyme attached to the membrane of cells located in the intestines, kidney, testis, gallbladder, and heart. ACE2 lowers blood pressure by catalyzing the hydrolysis of angiotensin II into angiotensin.

They're (viruses) thermodynamically attracted to people who have more inflammation for them to use for their fitness (fuel). These high expressed ACE2 (aka niacin receptors) along with the SR-B1 coreceptor right next to it - they (virus) sneak in this.

Note:
SR-B1 is a scavenger receptor class B type 1. It functions as a receptor for high-density lipoprotein. It is also know as CD36, a scavenger receptor class B member 3.
SR-BI/CD36 chimeric receptors define extracellular subdomains of SR-BI critical for cholesterol transport
https://pubmed.ncbi.nlm.nih.gov/25211142/

The SR-B1 is where HDL dumps off cholesterol from blood into tissue to prevent atherosclerosis. Because the cholesterol was leaking out of the tissue after it reached threshold, it can not contain it anymore due to too much pressure. As a result, HDL lowers because it's not getting developed in the liver anymore. The HDL has to attend to scooping more cholesterol back into tissue, and is used up real quick.

The virus then gets in cells and as it literally continues to consume your energy until it reaches a threshold it needs of energy to double (replicate). As it does this it depletes melatonin. It also makes it a lot easier if you have deficient melatonin. You can see now why unhealthy and older people who have not had enough melatonin and niacin as most at risk. They also have low HDL/high TG (triglycerides). The depleted melatonin makes the PDC receptor, already stunted from accumulated inflammation over a lifetime, from pyruvate to Acetyl-CoA even more stunted. Due to this melatonin gets gradually even more depleted into say long haul COVID. As soon as the virus meets threshold to replicate it moves out the mitochondria, and on to the next one (cell) like a bad ex-girlfriend. Repeat forward. This is why COVID long haulers flush like crazy with even 50 mg doses of niacin.

Note:
• Type I interferons (IFNs) derived from plasmacytoid dendritic cells (PDCs) are critical for antiviral responses
• Pyruvic acid or pyruvate is a key intermediate in the glycolytic and pyruvate dehydrogenase pathways, which are involved in biological energy production.
• Acetyl-CoA is a molecule that participates in many biochemical reactions in protein, carbohydrate and lipid metabolism.

As the virus leaves each cell, it and all the crazy inflammation it amplified [hypered], leaves melatonin depleted and stunts further the PDC from pyruvate to acetylCoA. This is needed for AAANAT receptor from tryptophan to serotonin to melatonin stunted too, and so melatonin isn't made more and more.

Note:
The key regulatory step in melatonin synthesis is catalyzed by arylalkylamine N-acetyltransferase (AANAT), which converts serotonin to N-acetylserotonin.

This leaves ACE2 downregulated, and happens especially in the intestines/colon.

This is how the virus/spikes - like IVM gains easy access to your brain/nervous system then - your gut becomes leaky with this ravaging of melatonin and inflammation. This gives easy access through the Vagus nerve to cross into BBB (blood brain barrier) and nervous systems where the most bang for the buck energy is for them.

Basically the virus/spikes have to deplete your already deficient melatonin and niacin to succeed and be thermodynamically attracted in the first place.

So keeping NIATONIN sufficient/repleting it takes back control of YOUR energy metabolism that the spikes try to take over for their food (energy).

It (NIATONIN) doesn't just push out inflammation. It allows T-cell differentiation (melatonin through ACE2 aka GPR109A expression). Then niacin comes in which is literally an innate/mandatory function of the recruitment and facilitation of T-cells, killer cells, and B cells. It induces phagocytosis, denatures, kills, and clears the virus as well as all pathogens and all toxins. It's a feasting grounds for them.

Note:
GPR109A (encoded by Niacr1) is a receptor for butyrate in the colon. GPR109A is also a receptor for niacin, which is also produced by gut microbiota and suppresses intestinal inflammation.
https://pubmed.ncbi.nlm.nih.gov/24412617/

What To Buy

NIACIN: https://purebulk.com/products/niacin-vitamin-b3-immediate-release?sca_ref=1004090.8JspdBHd04…

MELATONIN: https://purebulk.com/products/melatonin?sca_ref=1004090.8JspdBHd04…

Precision (0.000 g) Scale: https://purebulk.com/products/gemini-20-digital-scale?sca_ref=1004090.8JspdBHd04…

DOSING

This graphic contains the protocol. Please read it all, especially the top portion where is says to eliminate certain things while using the protocol.

HOW TO FLOW CHART

[17strings]

Interesting meme. I’d seen it earlier. I wonder who made that connection? I had to verify it from other sources to make sure it wasn’t edited, but it appears to be legit. I wonder if there was ever one for niacin. ;)

And yes, we are certainly each an experiment of one. I have a second experiment of one just underway - one of my cats. She has a chronic condition that is helped by lysine supplements when it flares up, and I decided to try her on niatonin. I gave her around 7 M and 50 N to start. I wonder if cats flush? She seems comfortable enough. We’ll see.

[17strings]

It gets crazier
——————+
Whoops, just saw you linked the article about the niacin one! But there is no picture of it! Now I have to sleuth some more. :(

[17strings]

Just read on FR about research being done with nicotine to cure covid.

---

I remember hearing somewhere that coof sufferers who smoke fared better than non-smokers, which seemed very backwards and non-intuitive at the time, because of the lungs and all... but that’s verrry interdasting.

[21twelve]

I’ve looked into it a little bit. They of course say not to take up smoking to prevent covid! Smokers that DO get covid symptoms do a lot worse because their lungs are already damaged.

I used to smoke a lot. I would be afraid of getting hooked on nicotine again through the gum or patches. The article talked about using ivermectin in conjunction with nicotine.

[AZLiberty]

Over 11 doses and 6 days, I’ve been keeping niacin at 500 mg and gradually raising the melatonin from 6 mg to 200 mg and the time interval between melatonin from 0 to 40 minutes. My initial flush was a hot one, including gold spots in my visual field and a decline in blood pressure to 78/53.

At 150 melatonin I still had mild flush sensations at the ears, the forearms, and the upper back. At 200, I now have only mild flush at the ears.

At this point do I just accept the mild flush at the ears and start increasing the niacin, or is it really important to completely quash the flush?

[AZLiberty]

My brother had been having serious flush systems even with relatively high levels of melatonin. This evening he did 65M/500N with a 90-minute delay in between. He experienced no flush when he took the niacin, but an hour later he said his cheeks, eyebrows, and shoulders started to glow a bit.

How long is it supposed to take the melatonin to process through the liver?

[Tennessee Conservative]

That is crazy.

[numberonepal]

My 75 pound old dog is on 50M/600N and I can’t tell if she flushes or not. But I do know some of her spunk is returning.

[numberonepal]

[numberonepal]

It’s really important to quash the flush. The sweet spot is key. However, you can double that dose and add a little more mellie. For example: 500M/1000N and see what happens. If you get groggy, and more niacin. If you flush add more mellie.

[numberonepal]

90 mins is too long. 10-30 mins is the recommended time. And he's probably not to near enough mellie.

[17strings]

I just found this other image of the niacin crop circle which is diagrammed a little clearer. Wish I could post it here directly, but haven’t got that superpower! (Maybe that will come, with moar mellie? lol)

https://t.me/vaccinereversal/76141?embed=1

[17strings]

Looking further, I found this clearer picture of the Niacin circle before it was defaced:

And here is an interesting blog post I found about the Melatonin crop circle
(it won't let me post its images here either, hmmm!):

http://www.cropcircleuniversity.com/2011/07/23/2011-07-23-roundway-hill/

[AZLiberty]

For Dose #12, just did 500M/1000N. Warm tingly ears and forehead, slightly red face, warm and itchy forearms.

I’ll try 600M/1000N this evening.

[numberonepal]

[numberonepal]

IVERMECTIN CONVERSATIONS IN THE CHAT AND THE GABA RESET PROTOCOL
Hello newcomers! This is a room where we discuss the Niatonin Protocol. We appreciate everyone who comes in here looking for improvements to their health and well being. We don’t want to seem like we don’t want to hear about your experience using Ivermectin. We do. But this is an environment for healing from toxic pharmaceuticals. If you had a good experience with Ivermectin, then that is your choice. Unfortunately, there are hundreds of people in here that have not. Please refrain from conversations about or in support of Ivermectin while in this chat. If however, you are here to ask about ways to recover from neurotoxicity due to the use of Ivermectin, we have resources for you:

IMPORTANT: For GABA receptor treatment:
(Stop Niatonin during this)
- 400mg l-theanine
- 500-700mg GABA
2X day for 1 - 6 days

Note: “60% of the general population has some degree of this mutation, which essentially messes up GABA receptors” - Dr Kats

Consider doing this if you have, or been treated for (incomplete): anxiousness, anxiety, schizophrenia, autism, depression, major depressive disorder.

Further consider if you see: expressive language impairment, hypotonia, sleep disturbance, Inattention, hyperactivity, OCD (obsessive compulsive disorder), hyperreflexia, psychomotor issues, high pitched cry or spasticity.

Seek expert advice if you have a history of seizures, alcohol misuse, barbiturate use, benzodiazepine use or GABA related issues: Niatonin.youcanbook.me would be my first step!!

Sources: https://otter.ai/u/dHAOPb-CTrhehj37kxwO0injnXw

https://otter.ai/u/7r79qmTx3MI9CUotWwhXR1Z9fK4

https://otter.ai/u/jJ6rUHgRfHsJhuJWMbtzBJUFkgU

https://www.ncbi.nlm.nih.gov/books/NBK526124/

[numberonepal]

[numberonepal]

[Yaelle]

I don’t understand any of this. Melatonin gives me a strong migraine.

[Yaelle]

I bathe in mag flakes nightly.