In a way, this hinges on Roe v Wade. Can I make medical choices? Do I control my body? At the federal level, does the Constitution give me this kind of power? Or is it a state decision with the Constitution playing no role at all?
I think mandatory vaccines AND abortion should be decided by your state legislature.
Do I control my body?
There may lie the difference. With abortion, the question is actually Do I control my body AND the body of another?
Um.... apples and oranges. Unless you make it mandatory vaccines AND MANDATORY abortions.