My understanding is that cell division is programmed in to only happen so many times and when the last batch wears out you die. SO perhaps we are not looking at an eternal life pill, but an lifelong youth pill.
The mystery of cell division is not well understood.
Cellular senesence was a big step, but why it happens is unclear.
No doubt it has to do with the telomeres. But it also has to do with the mitochondria. And aging in general “kluges” up the cells with various kinds of debris that the cells don’t exactly know what to do with.
One thing that can reverse it - at least some of it - is carnosine.
I’ve studied these issues alot, I already took about a months worth of NAD+, didn’t make me feel any different, but who knows?
Epigenetics probably play a role.
I’m 62 years old, just in interest of full disclosure.