Absence of Mitochondrial Proteins May Prevent Age-Related Diseases, Increase Lifespan

Daily Tech ^ | May 12, 2011 | Tiffany Kaiser

[decimon]

Researchers hope to control a group of mitochondrial proteins that attack and damage other functional cell parts, which leads to age-related diseases

Thomas Nyström, study leader and a researcher in the Department of Cell and Molecular Biology at the University of Gothenburg, and a team of researchers, have discovered that a group of mitochondrial proteins may be responsible for age-related diseases.

Scientists have theorized that the mitochondria, which are the power stations of cells, are responsible for human aging. This theory comes from the fact that mitochondria not only produce the body's energy, but also create harmful byproducts. These byproducts are reactive oxyradicals, and they attack several other parts of the cell. When a cell is attacked, it could become permanently damaged, which forces it to discontinue the operation of important functions. In the theory's conclusion, the lack of certain functional cells over time causes the organism to age.

Now, Nyström and his colleagues have found that these mitochondrial proteins, called MTC proteins, may play a crucial role in age regulation in humans. The proteins are traditionally apart of mitochondrial protein synthesis, but have other roles that impact genome stability.

[decimon]

Mitochondria

[decimon]

Ping

[Signalman]

Sign me up.

[Dead Corpse]

The line forms to the left...

[EyeGuy]

I’m gonna go out on a limb and say that this is an oversimplification of a MUCH more complex process.

Shutting down these proteins from the powerhouse of the cell is a Pandora’s Box.

[Captain Rhino]

Old age - something else to blame on your mother...and her mother...and her mother ...and ...

[N-R-T]

There you have it: eliminate all free radicals.

[SunkenCiv]

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[TheOldLady]

Cue the “Never Say Never Again” music.

[ApplegateRanch]

...and a timely abscence of Mittochondrial jeans might cancel another RINO out of the presidential race.

[668 - Neighbor of the Beast]

Yeah, blame Eve! How original!

[bannie]

First the apple...now mitochondria. It's always the woman's fault.

[1010RD]

All men wish for a long life, but no man would be old.

[1010RD]

Old age itself is a disease.

[1010RD]

Old age itself is a disease.

[colorado tanker]

Maybe they're related to midichlorians. Most of the people with high midichlorian counts didn't make it past Episode Three.

[SunkenCiv]

If the movies had been shot and released in chronological order, I wouldn’t have made it past episode one. :’)

[SunkenCiv]

Chicks.

[SunkenCiv]

That hasn’t worked in Italy.

[SunkenCiv]

Life is an embarrassment of riches, and alas, best appreciated in retrospect.