Strong men will answer the call again, just as they did in 1861.
And if it's like 1861, sorry, unscrupulous and power hungry politicians will be making the call and leading it from the rear. As Oliver P. Temple, a man who personally knew many of the secessionist leaders said:
The most powerful (motivation for secession), as it always has been, in revolutionary movements, was personal ambition. There was something peculiarly fascinating to bold, ambitious men in the thought of forming a great slaveholding confederacy, embracing fifteen states over which they would bear sway; with an aristocratic class to support their authority; with cotton, the greatest wealth-producing staple the world has ever known, as the basis of unparalleled prosperity, and with an obedient, servile race to perform all labor, and minister to the comfort and wants of this superior class as long as governments should last. Of course this motive was concealed...