No, it wouldn’t. But physical evidence can point toward non-physical realities.
Tell me about your thoughts, for example, or your feelings. They’re invisible. Are they therefore not real? Does science have nothing to say about your thoughts and feelings? Or can we come to some understanding of these non-physical things through the use of science?
Does PMS and 'roid rage exist in your world? Hormones are chemicals. They are the source of emotions. Emotions are the carrot and stick along with pleasure (endorphins) and pain that helps drive positive evolutionary behavior absent discretionary memes.