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Opioids are the gold standard for treatment of chronic and acute pain; however, their use may result in significant gastrointestinal side effects, including nausea, vomiting, and constipation. A new study is the first report of how opioids like morphine cause gastric inflammation and how this condition can be reversed through treatment with proton pump inhibitor drugs like omeprazole, an over-the-counter medication commonly used to reduce stomach acid. Opioid users, compared with non-users, have a higher incidence of gastric dysfunction, greater levels of gastric retention, worse quality of life, increased hospitalizations, and increased use of antinausea and pain medications. To investigate...

A study reveals new insights into how gastric cancer develops and suggests a preventive treatment. Eunyoung Choi, Ph.D. identified for the first time that Trop2+/CD133+/CD166+ dysplastic stem cells are a key source of clonal evolution of dysplasia to multiple types of gastric cancer. Their investigation further showed that pyrvinium, a commonly prescribed treatment for intestinal pinworms, blocked regeneration of dysplastic stem cells by controlling the CK1a signaling protein in mouse models and in human organoids. "The dysplastic stem cells that we identified are de novo stem cells first present during carcinogenic transition of pre-cancerous metaplasia to dysplasia in both mouse...

April 27 (UPI) -- A health-related report that examines numerous issues for American families, such as wages and rising costs, said on Wednesday that economic security is out of reach for many people in the United States -- particularly women and women of color who are still at a fiscal disadvantage compared to men. The assessment, the 2022 County Health Rankings & Roadmaps report, looks at a number of key issues facing working Americans and found that most need a pay increase of more than 70% before they can earn a living wage. At worst, in some counties across the...

SAN FRANCISCO (AP) — Members of California’s first-in-the-nation reparations task force convened in a historic African American church in San Francisco on Wednesday, making their own history as they work to educate the public and develop a restitution proposal for the people harmed by the institution of slavery. The two-day meeting at the Third Baptist Church in the city’s Fillmore district was the first time the nine-member task force gathered in person since its inaugural meeting nearly a year ago. The meeting comes mere weeks after the group voted to limit restitution to descendants of enslaved Black people. Morning attendance...

Former President Obama exhorted House Democrats to celebrate their accomplishments on the campaign trail, rather than dwell on the setbacks they've faced, as they try to defend their slim majority in the midterm elections this year. Obama, the featured keynote speaker during the caucus' virtual messaging summit Thursday, told lawmakers to "take the wins you can get" and it "doesn't help to whine about the stuff you can't change," according to two sources familiar with the conversation. He argued that they have a more compelling message in selling what their legislative successes mean to voters, rather than campaigning from a...

While the Biden administration has once again extended the pause on student loan repayments, some progressives have said that unless more is done, it could cost Democrats in the midterms in 2022. The progressive wing of the Democratic Party is sounding the alarm over potentially losing voters and subsequent races if the campaign promise of canceling student loan debt goes unfulfilled by the Biden-Harris administration. Before the pause was extended, several prominent Democrats voiced their concerns about payments starting again and how it could cost them the midterms. Natalia Abrams, president of the Student Debt Crisis Center, a nonprofit focused...

New research into how a common parasite infection alters human behavior could help development of treatments for schizophrenia and other neurological disorders. Scientists say behavior changes in those infected with T. gondii, which currently infects 2.5 billion people worldwide and causes the disease Toxoplasmosis, could be linked to lowered amounts of norepinephrine, a chemical released in the brain as part of the stress response. Norephinephrine also controls neuroinflammation, the activation of the brain's immune system against infection. Norepinephrine and neuroinflammation are associated with neuropsychological disorders such as schizophrenia, Alzheimer's disease, and ADHD. T. gondii can only sexually reproduce in cats....

Some Wisconsinites may know cannibal sandwiches because they're a family tradition — or because of the warnings from the Centers for Disease Control and Prevention. Cannibal sandwiches are a Midwest staple. Consisting of fresh raw beef on rye bread topped with chopped onion, and a sprinkle of salt and pepper, the dish makes some squirm and others lick their chops. Last December, the popular dish even gained international attention with a tweet from the Wisconsin Department of Health Services that warned against eating raw meat. But where did the tradition come from? Why is it so popular in Wisconsin?

Toxoplasma gondii, a microscopic parasite that gets inside our cells, is present in about 10 percent of the population in the U.K. But in tests on lung cancer patients, all were found to be infected with the parasite. "It's a remarkable result which we don't fully understand yet," states Geoff Hide, Professor of Parasitology at the University of Salford. "It is possible that the presence of the parasite in these patients is exacerbating their symptoms of cancer or interfering with their therapy." Working with Professor Dave Singh, clinical consultant at the Medicines Evaluation Unit at Manchester University, they tested 72...

Thirty-five groups of doctors, research scientists and lawyers across US, UK, Germany, Austria and Japan examined a thousand vials of Pfizer, Moderna and AstraZeneca ‘vaccines’ and found hundreds of sharp edged metal pieces in one droplet along with parasite material. When researchers heated the samples while being observed under the microscope, the particles began to move and were in-sync with each other. Sharp metal objects, graphene layers, large rectangular objects that have never seen before, are not biologic and likely are harmful when inside a human body. These doctors are calling for a worldwide halt of Covid injections. -GEG

Myriad failed programs show that our government and its many employees have goals entirely separate from the welfare of America and her citizens. Reagan once said: "The nine most terrifying words in the English language are: I'm from the Government, and I'm here to help." He was right, the government’s not your friend and it most certainly isn’t here to help you. The dirty little secret about government is that its purpose is not really to make the lives of citizens better but, rather, to accumulate power at the expense of citizens. Not sure about that? Ask yourself, how many...

CHICAGO — A historian devoted to keeping alive the stories of long-dead victims of racial violence along the Texas-Mexico border and a civil rights activist whose mission is to make sure people who leave prison are free to walk into the voting booth are among this year’s MacArthur fellows and recipients of “genius grants.” The Chicago-based John D. and Catherine T. MacArthur Foundation on Tuesday announced the 25 recipients, who will each receive $625,000. Race figures prominently in the work of about half of them, including that of Ibram X. Kendi, author of “How to be an Antiracist” and “Stamped...

Great video exposing the truth and the effectiveness of a very inexpensive treatment for Covid 19.

NEW: Frito-Lay workers reveal that they’ve worked up to 5 months straight without a day off, and that multiple coworkers—driven to exhaustion—have died by suicide. Their strike in Topeka is gaining nationwide attention. Now Frito-Lay workers in other states are speaking out. pic.twitter.com/yppQ8iPn3n — More Perfect Union (@MorePerfectUS) July 19, 2021 Forced overtime at Frito Lay. Full details here… https://www.wibw.com/2021/07/16/frito-lay-says-strike-unnecessarily-puts-employees-risk-hardships/

Tokyo (AFP) - Athletes at Tokyo 2020 will be allowed to "express their views" before and after competing -- but not on the podium -- after Olympics chiefs relaxed some of the rules for protests at the event. The International Olympic Committee (IOC) released new guidelines Friday softening a long-standing ban on political protests at the Games. It means athletes will now be allowed to take the knee before play begins to highlight racial injustice, speak to the media and post online about their views, or wear clothing with a protest slogan at a press conference. But political statements during...

By November 1947, as Jews continued their process of building and Arabs continued their process of hating, the United Nations gave the green light to establish a Jewish state and an adjacent Arab state. Jews accepted the U.N. partition of the region, declaring the new state of Israel in May 1948, but the Arabs rejected the plan and attacked the newly declared Jewish state. Israelis fought and miraculously prevailed in its War of Independence, and the project of rebuilding the ancient homeland moved forward. Now it is an officially recognized member of the community of nations. Compared with the desolation...

Fox News is not recovering from their Post-Steal ratings collapse. Going from record ratings before their duplicitous Arizona call, to their massive ratings collapse by Tuesday 1/12. Here are the current Fox News ratings losses since The Steal according to Nielsen as of Monday 1/12: MacCallum -52% Ingraham -52% Hannity -52% Baier -52% Bream -50% Sandra Smith -49% Fox and Friendless -48% Outnumbered -46% Carlson -44% Cavuto -44% The Five -38% Hemmer -34% Perino -32%

New York Gov. Andrew Cuomo (D) repudiated the state's debt and vowed "not to pay a single cent of it. Every prior president and congress has recognized that New York is America's 'trophy wife' and covered the losses incurred in running this country's greatest state. It is only Trump and the Republicans in congress who are now balking at bearing a burden gladly accepted by both Parties prior to now." The City of New York has a current $9 billion shortfall. The State of New York has a $30 billion shortfall. These gaps were created by the combined profligacy of...

An Australian drug known as Ivermectin, which is already in use throughout the world to treat parasitic conditions, is showing great results in killing coronavirus in studies involving patients, (according to Sky News.)"Because I'm involved in developing these in the U.S. where all the patients are, there are a number of studies that are amazingly successful. We're talking close to 100%. In fact, we haven't seen a result yet under 100%. It looks like corona is very simple to kill," Professor Thomas Borody, medical director of Australia's Center for Digestive Disease. "It's available as a prescription medication. You wouldn't use...

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