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UK scientists create embryo with three parents
The Times of India ^ | 6 Feb 2008, 0005 hrs IST | The Times of India

Posted on 02/05/2008 11:24:18 AM PST by CarrotAndStick

For procreation, it has always taken two to tango. But scientists from the UK's Newcastle University have taken reproductive biology where it has never gone before - creating a human embryo from three parents, two women and a man.

The scientists believe the technique will help prevent women with diseases of the mitochondria - tiny batteries within each cell that provide energy - from passing on the defects to their children. Mitochodrial DNA is carried from mother to offspring and faults in it can cause about 50 known diseases, some of which lead to disability and death.

Researchers from Newcastle University presented their findings at a medical conference at the weekend, a university spokeswoman said on Tuesday.

According to reports in the British media, the Newcastle team has created 10 successful three-parent embryos from couples at risk of mitochondrial disease. The embryos were fertilized through the conventional in vitro method.

After a day, each embryo was emptied of its pronuclei - structures that contain the sperm and egg which are still separate at this stage. These pronuclei were inserted into an emptied egg from a second woman with healthy mitochondria.

In this way, the team created embryos which contained genetic material from the original parents but had healthy mitochondria from the donor woman.

The embryos grew normally till the fifth day, after which they were terminated.

If the embryos were to be implanted back into the mothers, they would have created the world's first genetically modified babies. The team's experiments with mice have produced healthy offspring.

Professor Patrick Chinnery, a member of the Newcastle team, was quoted by the BBC website as saying: "We believe from this work, and work we have done on other animals that in principle we could develop this technique and offer treatment in the foreseeable future that will give families some hope of avoiding passing these diseases to their children."


TOPICS: Extended News; News/Current Events; Technical
KEYWORDS: biology; embryo; genetics; reproduction

1 posted on 02/05/2008 11:24:25 AM PST by CarrotAndStick
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To: CarrotAndStick

One parent, two parents, three parents or ten parents, these embryos are human beings just like you and I.


2 posted on 02/05/2008 11:27:11 AM PST by trumandogz
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To: trumandogz

About Millions of “parents”? A “people’s” child. Of course, since it can’t be parented by so many people, it will be owned by government./socialst utopia


3 posted on 02/05/2008 11:32:44 AM PST by SolidWood (Romney/Thompson 2008 - Save the Republic!)
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To: SolidWood

All People are Equal

All Embryos are Equal


4 posted on 02/05/2008 11:34:05 AM PST by trumandogz
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To: CarrotAndStick
"The embryos grew normally till the fifth day, after which they were terminated. "

killing humans to proove something can be done. how noble.

5 posted on 02/05/2008 11:34:05 AM PST by robomatik (......uh since fred and duncan are out, i think i need a new tagline. =()
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To: CarrotAndStick

Imagine the confusion this child will face when trying to identify where he/she comes from?


6 posted on 02/05/2008 11:36:32 AM PST by texas_mrs
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To: texas_mrs

This kind of research is crossing a line into areas where we shouldn’t go, in my opinion. When people don’t have any morals, ethics, or values, this is when they dream up research such as this to participate in.


7 posted on 02/05/2008 11:40:05 AM PST by Dilbert San Diego
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To: CarrotAndStick
The embryos grew normally till the fifth day, after which they were terminated.

"Terminated" is so much easier to say than "murdered."

8 posted on 02/05/2008 11:41:29 AM PST by pax_et_bonum (That midget hates it when I do that.)
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To: CarrotAndStick

Heather really will have two mommies.


9 posted on 02/05/2008 11:42:10 AM PST by USFRIENDINVICTORIA
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To: CarrotAndStick

Three parents?

They’ve created another Chelsea Clinton?


10 posted on 02/05/2008 11:58:06 AM PST by PBRSTREETGANG
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To: PBRSTREETGANG
Three parents? They’ve created another Chelsea Clinton?

Darn you! You beat me to it!! ;-)

11 posted on 02/05/2008 12:02:59 PM PST by Digital Sniper (Hello, "Undocumented Immigrant." I'm an "Undocumented Border Patrol Agent.")
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To: SolidWood

Well, my kids all had about a million potential ‘dads’ going for the gold.


12 posted on 02/05/2008 12:07:26 PM PST by Blood of Tyrants (G-d is not a Republican. But Satan is definitely a Democrat.)
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To: texas_mrs

A politician because they will be two faced.


13 posted on 02/05/2008 12:08:01 PM PST by Blood of Tyrants (G-d is not a Republican. But Satan is definitely a Democrat.)
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To: CarrotAndStick
...creating a human embryo from three parents, two women and a man.

Why would you want to do something like this? My take is that it will improve families' chances of affording the college tuition rates of tomorrow. The Ivy League schools will probably start subsidizing this research to assure themselves of a new generation of students.

14 posted on 02/05/2008 2:11:29 PM PST by BlazingArizona
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To: CarrotAndStick
This sounds like they are only using the healthy woman's cell as a carrier, and that none of the actual chromosomes come from her. I believe, though it's hard to understand, that this AS USED IN THIS ARTICLE is not cloning nor is it any "weirder" that a donated heart or kidney.

I am very sad though that they made these babies, children ONLY of the two parents who wanted them, and then killed them. Heartbreaking.

15 posted on 02/05/2008 2:15:42 PM PST by Yaelle
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To: CarrotAndStick

Gattaca

http://en.wikipedia.org/wiki/Gattaca


16 posted on 02/05/2008 3:19:28 PM PST by MD_Willington_1976
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To: Yaelle

The mitochondria is from the second woman.


17 posted on 02/05/2008 7:13:29 PM PST by CarrotAndStick (The articles posted by me needn't necessarily reflect my opinion.)
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