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COVID-19 Vaccine: What Side Effects — or No Side Effects — Mean; Everyone's body responds to vaccines differently.
Discover Magazine ^ | 03/23/2021 | Leslie Nemo

Posted on 03/23/2021 9:33:51 PM PDT by SeekAndFind

If you’re gearing up to get your COVID-19 vaccine, maybe keep your schedule light for the day after your second shot — or only shot, if you’re getting the Johnson and Johnson variety.

Some people feel muscle aches, pains or just flat-out exhaustion afterward, side effects that other vaccines prompt in people, too. “These are not unexpected,” says Carlos Malvestutto, an infectious disease physician at Ohio State University Wexner Medical Center. “We see them to a higher or lesser extent with pretty much every vaccine.” And while who feels what symptoms and when might surprise some people, the way the side effects are playing out now that millions are getting vaccinated lines up with what a lot of medical professionals expected to see.

How You Know the COVID-19 Vaccine Is Working

First things first: “That reaction is not having COVID-19,” Malvestutto says. The vaccines can’t bring you down with the infection — they only supply snippets of the coronavirus itself, and you’d need the entire virus to make you sick. Instead, any aches, arm tenderness or fatigue you might feel a day or two after the shot comes from your immune system doing what it’s supposed to: Learn how to fight off a real infection.

In the Moderna and Pfizer vaccines, for example, the shot introduces into your cells pieces of mRNA, the instructions for your body to make a protein from the surface of a coronavirus. Once your cells start churning out the virus protein, your immune system recognizes the particles as something that doesn’t belong to you. Flagging the proteins down as undesirable kicks off a campaign to eliminate them, which can come with all the symptoms of an activated immune system — aches, sore muscles, and feeling rundown.

Why You Got Bad Side Effects and Grandma Didn't

Not everyone might feel the same side effects, or any at all. Malvestutto said that he, for example, felt some chills after getting his vaccine, while his wife, another physician, felt under-the-weather for longer. In some cases, older individuals have fewer side effects after the vaccine. This may sound counterintuitive — these same people are more likely to get seriously ill or die from the virus — but the lack of aches and pains proves why seniors were a priority for a vaccine, Malvestutto says. Feeling as if nothing happened after the injections could mean your immune system isn’t quite as easy to activate. You might not respond to the real virus with as much vigor, a situation that is more likely to be true for immune systems that have been working hard for, say, 70 years. That being said, someone doesn’t have to feel like they have the flu after the shot in order to develop good resistance to the actual virus.

People receiving the two-shot vaccine might also notice that they only feel run down after the second one — another expected pattern, Malvestutto says. If the first injection tees the immune system up, the second shot is the follow-through swing that sends the ball flying, as the follow-up dose is when the body gets exposed to much more of the protein it now knows to attack. “The second shot comes into a primed body that recognizes [the protein] and goes to work,” Malvestutto says. The two-part act also explains why people who are exposed to the virus between injections — or within a couple weeks of the second dose — might get sick. It takes time for your immune system to build up enough defense tools after the second shot.

If someone feels the weight of the symptoms after the first dose, that could be a sign they were already infected with the virus, Malvestutto says. Studies have found that people who were previously sick with the coronavirus developed side effects and larger immune responses one dose in, meaning their immune system was already in the “teed up” phase. “They already have some antibodies, so half the work is already done,” Malvestutto says. The force of a single dose for those who already had COVID-19 has persuaded a few nations to consider dropping the second shot for previous patients.

The potential day or two spent wanting to stay in bed after the vaccine could be a small price to pay compared to coming down with the virus itself, Malvestutto says. Sure, a large percentage of people infected with the coronavirus never get symptoms. But some patients who had to get hospitalized for the virus — for a long time, that number hovered around 3.5 percent of all cases — as well as those who had more mild infections, are still reporting shortness of breath, chest tightness and other symptoms months after first falling ill. Estimates suggest up to one in 10 people who get sick with COVID-19 become “long-haulers,” or people dealing with symptoms for weeks to months.

And if you still have questions about what the vaccines do inside your body, that's okay. "Everyone has a right to get these vaccines," Malvestutto says. "Don't be afraid to voice concerns, and don’t keep concerns to yourself and quietly decide the vaccine isn't for you."


TOPICS: Health/Medicine; Science; Society
KEYWORDS: chinavirusvaccine; covid19; covidstats; mrna; sideeffects; vaccine
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To: kaehurowing
Had first shot. Moderna. No side effects except my upper arm and shoulder where I got the shot have been sore for a couple of days, like if you had been punched. Now on day 3 and the pain is almost completely gone.

According to the article, your body is now following external instructions to manufacture an alien viral protein. (But doesn't say when it stops doing so.)

How long before your develop into a full-blown "pod person?"

Regards,

21 posted on 03/23/2021 11:41:40 PM PDT by alexander_busek (Extraordinary claims require extraordinary evidence.)
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To: doorgunner69
Wife browbeat me into the moderna shot due to travel interests.

After the shot, were you issued a universally-recognized Covid passport, allowing you to now travel freely?

Can you now visit, e.g., Hawaii without having to be quarantined, etc.?

If not, then I suppose that this has done nothing to allow you to travel more freely, right?

Regards,

22 posted on 03/23/2021 11:45:18 PM PDT by alexander_busek (Extraordinary claims require extraordinary evidence.)
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To: Hardy Weinberg
This DNA-altering vaccine is not for me

mRNA isn’t the same as DNA, and it cannot combine with our DNA to change our genetic code. It is also relatively fragile, and will only hang around inside a cell for about 72 hours, before being degraded.

mRNA vaccines are based on the same ancient premise going on in our cells now and since the dawn of RNA: -- delivering mRNA into our cells, which they will use to manufacture a viral protein.

For instance, when we are infected with a virus - including relatively harmless viruses like those that cause the common cold - these invaders inject their genetic material into our cells, resulting in pieces of mRNA encoding viral proteins for the common cold being sent to our protein-making machinery.

The mRNA vaccines for COVID-19 work the same way as the common cold virus.

The mRNA Covid 19 vaccines provide instructions for making the same viral Covid-19 protein --- the coronavirus ‘spike’ protein used by the virus to gain entry to our cells.

Studies indicated that it was highly immunogenic, meaning if our immune cells encounter this protein, they will mount a strong response --- which should protect recipients against future COVID-19 disease. Once our cells have manufactured the viral protein, it is displayed on their surfaces where passing immune cells can spot it and respond.

Once inside the cell, the mRNA comes into contact with protein making-machinery located in the jelly-like cytoplasm filling the cell. It does not enter the nucleus, which is where our chromosomes (DNA) are stored.

https://www.gavi.org/vaccineswork/will-mrna-vaccine-alter-my-dna

23 posted on 03/24/2021 12:00:32 AM PDT by Right_in_Virginia ( )
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To: alexander_busek

Nonsense. I had my first Pfizer jab and I feel fine.

And so do I.


24 posted on 03/24/2021 12:14:53 AM PDT by Ken H (Trump won.)
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To: SeekAndFind

25 posted on 03/24/2021 1:35:56 AM PDT by Secret Agent Man (Gone Galt; Not Averse to Going Bronson.)
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To: alexander_busek

Texas is giving CDC issued cards with stickers that have your DL info(name , do number, Bday ECT. Plus your vax.manufacturer, batch number and vial number the second dose sticker has a QR code linking to the county or state database that your release form allows them to keep said info in and if you actually read it they are sending the info to the CDC as well. Which is good since only the CDC can issue yellow cards. What’s a yellow card?

It’s the CDC/WHO International Certificate of Vaccination or Prophylaxis.

You need one to get into any Central African country with a valid yellow fever vaccine but with the CDC covid database they will be issuing yellow cards by the millions upon request and you most certainly will need that yellow card for international air travel the EU is also working on yellow card databases the Israelis have theirs running and in phone app form. I have a yellow card from years of Africa work adding covid19 to it will be a nothingburger all th info was scanned at the vaccine site my DL both sides the vial and my entry QR code all with one of those hand held scan boxes like Wal-Mart uses with a camera and red laser code reader it was beep beep beep stab beep and print stickers with digital QR codes fast n efficient.


26 posted on 03/24/2021 1:44:12 AM PDT by JD_UTDallas ("Veni Vidi Vici" )
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To: Pelham

Second Moderna shot I call Mad Dog. I woke up at one AM with chills, fever, muscle pain, bed drenched in perspiration. It reminded me of my H1N1 2012 experience. It lasted about two days, and a couple of doses of Tylenol helped when the symptoms surged. I know for sure I didn’t get the placebo.


27 posted on 03/24/2021 3:18:46 AM PDT by Babba Gi
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To: SeekAndFind

And people think the government wi give us back the freedoms so many gave up because of a vaccine? Nope. Wear your masks. Hide. Bring in the third world. New variants. Fauci says.....


28 posted on 03/24/2021 4:51:18 AM PDT by Organic Panic (Democrats. Memories as short as Joe Biden's eyes.)
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To: JD_UTDallas
Name one vaccine a modern one as in under 25 years old that has had long term damages

We don't know their names because they were never approved by the FDA--as a result of long-term testing!
29 posted on 03/24/2021 5:48:11 AM PDT by cgbg (A kleptocracy--if they can keep it. Think of it as the Cantillon Effect in action.)
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To: SeekAndFind

I was wiped out the day after my 1st moderna shot. Headaches, body and joint aches, chills, fatigue. @nd shot coming up early April, I’m hoping it goes better.


30 posted on 03/24/2021 5:49:29 AM PDT by brooklin
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To: ThunderSleeps

Except these experimental gene therapy shots were rushed through after trials on just 0.013% of the US population over a span of several weeks.
`````````````
Perhaps they were pre-prepared, kinda like how gun legislation, overhaul of the medical system, reparations legislation rests dormant in a drawer until it is pulled out for use at the proper time for the prepared masses clamoring for it.

Was the Wuhan virus a product of ‘gain of function’ experimentation? It would be kinda handy if a vaccine ‘cure’ were prepared in tandem.


31 posted on 03/24/2021 5:57:52 AM PDT by smileyface ("The illuminati's whole philosophy demands the use, abuse, sacrifice and consumption of children.")
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To: House Atreides
Traditional vaccines are made from the virus itself. Grown in the lab, purified, then fragments (antigens) of the virus are processed into the vaccine. Once introduced to your body your immune system is triggered by the antigens and produces antibodies that kill any real virus that may enter your body. Your T cells have a memory and can typically re-make antibodies as needed. Known technology, been around for decades.

RNA is a messenger. Typically it carries instructions from DNA to cells telling them how to produce protiens etc. The RNA based vaccines are completely synthesized in the lab. They "program" the T cells to produce a response. Ok, sounds good - cut out the middle man, no risk from use of live virus, faster development, etc.

But we're literally programming an immune system response from a completely artificial stimulus. As I understand it, RNA vaccine technology has never before been put to widespread use. What if the RNA "program" misfires on some people, some combination of DNA? What if the RNA is damaged or degrades, can the program change? How good does quality control have to be in the manufacturing process? Can a rushed into production process meet that? Can the RNA program morph into a very different immune system response? How will it interact with people who have an auto-immune disease? As I understand it, we're still discovering variations of auto-immune diseases, so we don't even know comprehensively what's out there for the RNA to interact with.

The RNA based tech is probably, hopefully safe but... There will be side effects as we move into trials of this experimental (that's the FDA's classification) drug. But it is not really a drug, not really a traditional vaccine, it is literally gene therapy. Using genetics to invoke a response. Too many unknowns, yet we're performing widespread trials now - not on a few thousand volunteers spread over years as we study and look for side effects... Nope, tens of millions are now in the trial group. History and Murphy's law says we don't get that lucky as to be 100% successful on the first try. There will be side effects, there will be unintended consequences. Some of these may not, probably will not show up for years. By hanging the "experimental" moniker on the vaccines the FDA is protecting the pharmaceutical companies from any kind of liability. So if a large percentage of the people getting one of these RNA vaccines develop psoriasis or arthritis or some such in a few years, gosh, that's just too bad, suck it up, we'll fix that next time around...

So in this trial for the new technology I am going to self-select into the control group and not take the gene therapy. I may take the J&J vaccine in a few years (it is a traditional vaccine) if it does not show any significant side effects and if covid is still a thing.

32 posted on 03/24/2021 6:07:52 AM PDT by ThunderSleeps (Biden/Harris - illegitimate and everyone knows it.)
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To: SeekAndFind

ALL of the above-—is why I will refuse to get the vaccine. Last vaccine I got was Hong Kong flu-—and was laid flat for over 10 days. NO sick pay & NO INCOME.


33 posted on 03/24/2021 7:41:56 AM PDT by ridesthemiles ( )
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To: Right_in_Virginia; All

My reaction to my 1st Moderna shot (COVID-19 vaccine) was minimal. Slightly sore upper arm / shoulder. A bit of fatigue the next day. One oddity: The slight soreness felt as if it moved deeper - as if deeper than my actual shoulder joint, about 24 hours in. Then the 2nd day it moved back out to the muscles over my shoulder joint. By the 3rd day it was gone. My 2nd shot is scheduled a week from now.

My wife’s 1st shot resulted in minor arm soreness only. Her 2nd shot wiped her out the day after with fatigue, but, she was ok after that for several days until...

A week later she developed a body rash over her entire body. It scared the heck out of her, but went away overnight. I thought maybe she’d coincidentally developed a food allergy - likely fish or shellfish, which she eats a lot of. HOWEVER, I’ve now heard though a friend and through a relative of two people who developed shingles-like symptoms a week to 10 days after their 2nd vaccine shot, one Pfizer, the other Moderna. These symptoms lasted two-three weeks, evidently. I do not know if those were full-body rashes (shingles usually is not, but episodes of shingles typically are a few weeks long, or longer.) My wife’s Dr. (actually the head nurse @ the office) has not heard of such “delayed” rash or shingles-like reactions, but, again from friends and relatives, at least a few are saying this is a possible reaction. I wonder, though, about confusion with lesser injection site reactions that occur more quickly.

I’m not seeing anything online about these delayed by a week or more full body rashes, OR, shingles-like reactions. Has anyone else?


34 posted on 03/24/2021 8:52:53 AM PDT by Paul R. (You know your pullets are dumb if they don't recognize a half Whopper as food!)
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To: SeekAndFind

Felt I was forced to get the Pfizer vaccine by my transplant team. Took my first one on Monday. Fatigue started first. Yesterday I started with extreme joint pain, which I still have.


35 posted on 03/24/2021 9:13:09 AM PDT by KYGrandma
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To: ThunderSleeps

“...The RNA based vaccines are completely synthesized in the lab. They “program” the T cells to produce a response....”
***************************************************************************
Your post is on the money up until it gets to the 2nd sentence in the above extract. That sentence is incorrect and is where your post goes “off the rails” and into the woods with all kinds of scary “what ifs”. Actually the vaccines’ mRNA simply goes to the cells’ ribosomes (the cellular protein manufacturing “machines”) where it serves as the blueprint for manufacturing the necessary antigens. From that point on the immune systems react to the antigens (by developing the needed immunity) just as they do with more traditional vaccines. That’s all the mRNA vaccines do... just provide a different means to provide the needed antigens. It’s not really scary.


36 posted on 03/24/2021 9:49:23 AM PDT by House Atreides
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To: SeekAndFind

I had the Johnson & Johnson Vaccine administered to me Sunday at 11AM

Monday morning, as I went to work, my neck was a little sore, just like all those nights when my pillows are not quite right. No big deal.

In addition, I was pretty tired. I chose to leave work a couple of hours early, to get some rest, because I could!

Tuesday morning, I woke up feeling tremendous.

My suggestion is ‘don’t be a pussy!’
protect yourself, your friends, your family, and help get the country moving forward again, by getting whichever vaccine you can, when you can.


37 posted on 03/24/2021 10:26:10 AM PDT by PTBobW (Very minor side effects for me with J&J)
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To: House Atreides

Funny, I have sen 2 MDs in the last month—one my usual ,m annual check up and the 2nd—an infectious disease doc for a chronic condition. When the “vaccine” subject came up—BOTH said NO.. Thanks, but no thanks. I’ll take my MDs words over Fauxis “Doctor” claims any dasy


38 posted on 03/24/2021 10:27:06 AM PDT by freeangel ( (free speech is only good until someone else doesn't like it)
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To: alexander_busek

Trying to be dense or did someone piss in your post toasties?
No mention of passports or anything other than in your fevered little imagination.

Getting the shot was for the possible added help in fighting off the bug should I be exposed to it. We are planning on traveling to the mainland and back frequently.


39 posted on 03/24/2021 11:31:17 AM PDT by doorgunner69 ("Those who vote decide nothing. Those who count the vote decide everything.." -Joseph Stalin)
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To: doorgunner69

He suffers from a bad case Dunning-Kruger and insists on showing off his “intelligence.”


40 posted on 03/24/2021 12:21:01 PM PDT by StolarStorm
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