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Study finds smoking may damage your sperm (DNA germline mutations..)
Reuters on Yahoo ^ | 6/2/07 | Reuters

Posted on 06/02/2007 2:14:08 PM PDT by NormsRevenge

WASHINGTON (Reuters) - Here's one more reason not to smoke -- smoking may damage sperm, passing along genetic damage to a man's children, Canadian researchers report.

A study in mice shows that cigarette smoke caused changes in the DNA of sperm cells, the researchers said in this week's issue of the journal Cancer Research. Such mutations, know as germline mutations, are known to be permanent.

"If inherited, these mutations persist as irreversible changes in the genetic composition of offspring," said Carole Yauk of Health Canada's Environmental and Occupational Toxicology Division, who led the study.

"We have known that mothers who smoke can harm their foetuses, and here we show evidence that fathers can potentially damage offspring long before they may even meet their future mate."

Yauk and colleagues studied the stem cells that produce sperm in mice exposed to cigarette smoke for either six or 12 weeks. All male mammals continuously produce sperm.

They found 1.7 times as many DNA mutations in the cells of the smoke-exposed mice as in those of the unexposed mice after 12 week, and 1.4 times as many mutations after six weeks.

"This suggests that damage is related to the duration of exposure, so the longer you smoke the more mutations accumulate and the more likely a potential effect may arise in the offspring," Yauk said.


TOPICS: Health/Medicine
KEYWORDS: damage; dna; genetics; pufflist; smoking; sperm; study

1 posted on 06/02/2007 2:14:10 PM PDT by NormsRevenge
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REUTERS/File
Undated file picture of a man smoking.
2 posted on 06/02/2007 2:16:04 PM PDT by NormsRevenge (Semper Fi ... For want of a few good men, a once great nation was lost.)
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To: NormsRevenge

Then tell your little spermies not to smoke!


3 posted on 06/02/2007 2:17:09 PM PDT by Enterprise (I can't talk about liberals anymore because some of the words will get me sent to rehab.)
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To: Enterprise
tell your little spermies not to smoke!

Say What!?!


4 posted on 06/02/2007 2:21:40 PM PDT by NormsRevenge (Semper Fi ... For want of a few good men, a once great nation was lost.)
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To: NormsRevenge

I’m done with the procreation thing - leave me alone.


5 posted on 06/02/2007 2:24:18 PM PDT by WorkerbeeCitizen (I Relieve Myself In Islam's General Direction While I Deny Global Warming.)
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To: NormsRevenge

Not all mutations are bad. Most, but not all.

If it weren’t for mutations, we might still be apes, and we wouldn’t be sitting here reading FreeRepublic.


6 posted on 06/02/2007 2:26:14 PM PDT by AZLiberty (President Fred -- I like the sound of it.)
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To: AZLiberty
"If it weren’t for mutations, we might still be apes, and we wouldn’t be sitting here reading FreeRepublic."

What? Are you saying mutants read FreeRepublic?

7 posted on 06/02/2007 2:27:04 PM PDT by Enterprise (I can't talk about liberals anymore because some of the words will get me sent to rehab.)
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To: NormsRevenge
A study in mice shows that cigarette smoke caused changes in the DNA of sperm cells

Well... I guess it's a good thing that mice aren't men eh?

Both of my parents smoked and yet I'm healthy as a horse. My wife and I smoked and we brought forth four beautiful, healthy, talented, children.

Do my wife and I still smoke. No but my sperm worked just fine and none of my children nor my one grand-child are in any way deformed.

Amazing how the evidence never supports the conclusion of a junk-scientist isn't it?

8 posted on 06/02/2007 2:34:51 PM PDT by EndWelfareToday (Live free and keep what you earn. - Tancredo or Hunter)
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To: Enterprise

Oh my, I hope this doesn’t turn into a Crevo Evo thread. :-]

I mutate at the thought. :-}


9 posted on 06/02/2007 2:34:58 PM PDT by NormsRevenge (Semper Fi ... For want of a few good men, a once great nation was lost.)
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To: NormsRevenge

I think that’s Obama (seriesly).


10 posted on 06/02/2007 2:42:52 PM PDT by jdm (One of these days, I'm going to get rich doing something, but it probably won't be this.)
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To: NormsRevenge

This might shed light on how some sperm can be damaged by smoke.

11 posted on 06/02/2007 2:44:53 PM PDT by Enterprise (I can't talk about liberals anymore because some of the words will get me sent to rehab.)
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To: Enterprise

My mom smoked so much when she was pregnant with me that when I came out of the womb, the doctor had to cut four packs of KOOL’s off the umbilical cord.


12 posted on 06/02/2007 2:46:47 PM PDT by jdm (One of these days, I'm going to get rich doing something, but it probably won't be this.)
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To: Enterprise

Monica who?


13 posted on 06/02/2007 2:50:33 PM PDT by EndWelfareToday (Live free and keep what you earn. - Tancredo or Hunter)
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To: Enterprise

I haven’t had a thread in the Smokey Backroom for a long time. Thanks! lolol ;-)


14 posted on 06/02/2007 2:51:55 PM PDT by NormsRevenge (Semper Fi ... For want of a few good men, a once great nation was lost.)
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To: jdm

My Dad smoked 2 packs of Camel straights a day for years. Eight of us turned out OK, I reckun.


15 posted on 06/02/2007 2:54:32 PM PDT by NormsRevenge (Semper Fi ... For want of a few good men, a once great nation was lost.)
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To: NormsRevenge; pissant; martin_fierro

I wonder what happens to those who blow smoke rings?


16 posted on 06/02/2007 7:54:45 PM PDT by SunkenCiv (Time heals all wounds, particularly when they're not yours. Profile updated May 31, 2007.)
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