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Depression 'is NOT caused by low serotonin levels': Study casts doubt over widespread use of potent drugs designed to treat chemical imbalance in brain
Daily Mail ^

Posted on 07/19/2022 7:58:47 PM PDT by algore

Low serotonin levels do not cause depression, according to a major review.

Today's landmark findings call into question society's ever-growing reliance on antidepressants like Prozac.

Millions of patients take selective serotonin reuptake inhibitors

We believe this situation has been driven partly by the false belief that depression is due to a chemical imbalance.

'It is high time to inform the public that this belief is not grounded in science.'

One in six British adults and roughly 13 per cent of Americans take antidepressants, figures suggest.

NHS data shows there has been a surge in prescriptions doled out in England, with 8.3million patients taking them in 2021/22, 6 per cent more than the previous year.

The most common are SSRIs such as fluoxetine (Prozac), citalopram (Cipramil) and sertraline (Lustral).

Serotonin helps carry signals in the brain and is thought to have a positive influence on mood, emotion and sleep.

They are preferred to other types of antidepressants because they cause fewer side effects. Yet they can still lead patients taking them to experience anxiety, diarrhoea, dizziness and blurred vision.

Depressed patients can also be hit by crippling withdrawal symptoms when they try to come off the pills.

At the same time, a raft of studies have suggested they don't work any better than a placebo.

The UCL study, published in the journal Molecular Psychiatry, analysed 17 previous reviews dating back to 2010 and consisting of dozens of individual trials.

It does not prove SSRIs don't work. However, it does suggest the drugs don't treat depression by fixing abnormally low serotonin levels.

(Excerpt) Read more at dailymail.co.uk ...


TOPICS: Heated Discussion
KEYWORDS: depression; serotonin; ssri
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I wonder what these things could do to kids...

Probably we should just give them puberty blockers and booster shots instead

1 posted on 07/19/2022 7:58:47 PM PDT by algore
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To: algore

Covid


2 posted on 07/19/2022 8:03:15 PM PDT by Varsity Flight ( "War by the prophesies set before you." I Timothy 1:18)
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To: algore

Get rid of the d@mn pharmaceuticals. There are some in the population that might need them, but IMHO, they are over prescribed. Sometimes people have a problem that they need help with. How about we start with actual communication instead of drugging everybody?


3 posted on 07/19/2022 8:03:29 PM PDT by FamiliarFace (I wish “smart resume” would work for the real world so I could FF through the Burden admin BS.)
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To: algore

Low levels of Vitamin D.


4 posted on 07/19/2022 8:11:00 PM PDT by arthurus ( covfefei)
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To: FamiliarFace

“Sometimes people have a problem that they need help with. How about we start with actual communication instead of drugging everybody?”

Better yet, get them off their ass and off the junk food.

Exercise and nutrition will CURE it.

Think bootcamp...


5 posted on 07/19/2022 8:12:26 PM PDT by Mariner (War Criminal #18)
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To: algore

Interesting. Merits more time looking into this on my part.

It explains a LOT.


6 posted on 07/19/2022 8:15:32 PM PDT by logi_cal869 (-cynicus the "concern troll" a/o 10/03/2018 /!i!! &@$%&*(@ -)
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To: Mariner

Do you think everyone who takes SSRIs are fat and eat junk food and just sit on their asses?

LOLOLOLOL.


7 posted on 07/19/2022 8:20:26 PM PDT by FamiliarFace (I wish “smart resume” would work for the real world so I could FF through the Burden admin BS.)
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To: arthurus

Here’s my theory:

When you take a chemical to make you feel better...it works.

However, when and if you do NOT take the chemical, the depression, the hopelessness, the despair...RETURNS WITH A VENGENCE, worse than the original malady.

It wants to make up for the limited time when you felt happy.

But that’s just me.

I hope I never feel the need for them and I hope I am wrong about the return of the feeling down for other people.


8 posted on 07/19/2022 8:20:48 PM PDT by Maris Crane
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To: arthurus

Combined with lack of exercise and mobility…. Which explains the Vitamin D bcz people are fat and indoors.


9 posted on 07/19/2022 8:24:28 PM PDT by Levy78 (Reject modernity, embrace tradition. )
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To: Levy78

Yep, everybody on SSRIs are fat, lazy, and stay indoors. /s


10 posted on 07/19/2022 8:28:20 PM PDT by FamiliarFace (I wish “smart resume” would work for the real world so I could FF through the Burden admin BS.)
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To: arthurus

Yes.

Get out into the Sun, and find something productive to really care about and to occupy your mind.


11 posted on 07/19/2022 8:36:26 PM PDT by Jamestown1630 ("A Republic, if you can keep it.")
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To: arthurus

More sunshine?


12 posted on 07/19/2022 8:37:54 PM PDT by thinden (buckle up.....)
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To: FamiliarFace

Not everybody of course. They have their place and some folks need them…. many don’t.


13 posted on 07/19/2022 8:39:42 PM PDT by Levy78 (Reject modernity, embrace tradition. )
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To: algore

This news comes just in time. I deal with depression a lot. Even though I know the reality of Christ, my emotions and thought patterns are often negative. (What I’m trying to say is that I know based on the promises in God’s Word that my thoughts are not reality) I’ve been considering taking trazodone to see if that would help.

It didn’t help with the chemo nausea and so, I have little expectations of help now.

I will continue on my present course: crippling depression along with deep prayer during those times.


14 posted on 07/19/2022 8:46:47 PM PDT by Jemian (War Eagle! It is great to be an Auburn Tiger.)
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To: algore

“It does not prove SSRIs don’t work. However, it does suggest the drugs don’t treat depression by fixing abnormally low serotonin levels.”

Take home message.

If the drugs work, they work.

Saying that, if they actually work is debatable.


15 posted on 07/19/2022 8:48:10 PM PDT by ifinnegan (Democrats kill babies and harvest their organs to sell)
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To: Levy78

SSRIs aren’t helpful to many people, and instead cause problems that weren’t there. They are over-prescribed as a panacea. Exercise, eating right, and getting vitamin D help for sure, but there are many who actually have real trauma and abuse in their lives that they need help with. SSRIs don’t address this, and neither do diet, exercise, and sunshine. Some people need to talk about their trauma in order to move past it. I think there are many people who are mis-diagnosed as depressed but are really just tying to figure out how to right the wrongs that have happened. JMHO. I’m not a professional.


16 posted on 07/19/2022 8:48:17 PM PDT by FamiliarFace (I wish “smart resume” would work for the real world so I could FF through the Burden admin BS.)
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To: algore

History will one day record these decades of calling it a chem imbalance as witchcraft.


17 posted on 07/19/2022 8:50:44 PM PDT by lurk (u)
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To: algore

I suffered with it for 30 yrs before I started taking meds. The medication is a lifesaver. I tried everything. As for vitiman D, I take that too.

Its so easy to just say exercise by someone who has never suffered from it. Exercise is not a cure all


18 posted on 07/19/2022 8:51:33 PM PDT by roving (Blue Lives Matter More Than Children)
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To: FamiliarFace

The prevailing standard of care for clinical depression is medication combined with cognitive behavioral therapy. That will include lifestyle interventions such as improving diet, exercise, coaching on problem solving skills, social skills, etc.


19 posted on 07/19/2022 8:56:56 PM PDT by hinckley buzzard ( Resist the narrative.)
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To: hinckley buzzard

I agree with the cognitive behavioral therapy, but I think there are a lot of doctors who take the easy way out, and just prescribe, prescribe, prescribe. They don’t get to the root of the problem.


20 posted on 07/19/2022 9:04:55 PM PDT by FamiliarFace (I wish “smart resume” would work for the real world so I could FF through the Burden admin BS.)
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