[Darksheare]

My paint shop pro 7 can do that, just my mouse likes to do it's own thing. So a three minute GIF ends up taking thirty minutes and a couple aspirin.

And some people wonder why artists go mad or drink... *Chuckle*
You would probably have to bump your width and height up a bit as well as the resolution for a mouse pencil to work, then after you get it finished you could resize it. (Like making it 400x800 pixels and then resizing it once done. But doing a larger image takes more time and more frustration. So I am rather impressed with the little GIF people. I get too frustrated trying it myself.)

[MistyCA]

I do expand the image in order to create new parts and stuff, and then I shrink it back down. I literally do pixel by pixel. :)