[AntiGuv]

What is the evidence that those already predisposed to depression aren't (a) more likely to enter the 'rave' subculture; and (b) more likely to experiment with illicit drugs?

[walden]

I did a lot of study on it and talking to friends last year when I became concerned that my daughter was hanging out with the wrong people. There is a lot of the brain scan evidence-- the changes are visible. As to the long-term effects? Hard to know. I know this is just one small anecdote, but a friend of a friend of mine said that she only took it once, but felt that it had made permanent changes to her personality. Scary.

[Mamzelle]

Yes, it's hard to tell where the "indicator" stops and the "cause" begins.

[ffusco]

Good point. people who use tend to be depressed or emotionally unstable in the first place.