Ball's in your court . . .
The reason for the centralization of the federal government was not legislative; it was economic. It was a byproduct of the Industrial Revolution.
The IR centralized power in the hands of a few industrialists and bankers (yes, I know that sounds left-wing, but hear me out) because the kind of technology that enabled the kind of productivity gains that scale-economies crate were extraordinarily expensive. I mean here, massive factories, coal mines, coke mines, etc. Only a few people could afford to finance them. However, the economies of scale that they produced forced everyone with inferior cost structures out of business. Right? So most everyone was more or less working for a small number of people.
So, to counter the natural centralization that the IR brought, people had to organize and use the only instrument they had available--the Federal Government--to counter the centralizing power of industry. Modern day libertarians seem to have this weird idea that FDR took over in a putsch; he was elected four times, three times overwhelmingly. Why? Because people finally got a breakthrough, a way to control their lives which before had been more or less at the whim of industrialists.
Now, what does this matter? Well, guess what...the Information Revolution is unwinding the Industrial Revolution. The computer you're typing into has a massive amount of scale economic power. You have exactly as much scale-economic power in a computer to publish something that everyone in the world with a computer to see as the New York Times does. That's an awesome amount of power. Another example--fuel cells. Once fuel cells become widely available, people will need the public-energy structure less and less...because they'll have a private source of energy right in their homes.
The entire story of the 20th Century was the centralization of scale-economic power; the story of the 21st Century is the democratization of scale-economic power.
So, I'm not really worried about the "coming tyranny". The inexorable effect of the scale-economic revolution will be more federalism, lower taxes, etc. Individualizing technology will drive it in the same way as collectivizing technology drove the 20th Century.
What's the main danger? In the same way that collectivism united with industrial-revolution type technology to create all the atrocities of the 20th Century (the Holocaust, etc.), libertarian personalism will unite with individualizing scale-economic policies (think biotechnology) to create new kinds of horrors.
Evil and good start in the human soul; technology just amplifies which one we as a people choose.