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New drug relieves pain from Fibromyalgia
The Commercial Appeal ^ | 2/17/03 | NA

Posted on 02/17/2003 12:25:36 PM PST by GailA

New drug relieves pain from Fibromyalgia February 17, 2003

Conventional medications, such as Tylenol, Motrin or even morphine, provide little relief to sufferers of fibromyalgia, a mysterious and debilitating pain disorder. But a new drug might be able to thwart the nerve signals that scientists believe trigger the pain.

"This is a real breakthrough not only because it works, but it proves fibromyalgia can be treated," says Dr. Leslie Crofford, a rheumatologist at the University of Michigan in Ann Arbor who has studied the new drug, pregabalin.

The syndrome affects an estimated 5.6 million Americans.

Pregabalin reduces the release of specific brain chemicals, such as glutamate and noradrenaline, that may cause pain, says Terry Griesing, a neurology researcher with Pfizer Inc.

The drug, which still needs FDA approval, could be on the market as early as 2004.


TOPICS: Business/Economy; Culture/Society; Extended News
KEYWORDS: fibromyalgia; pain
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To: Ff--150
WhooHooo! Yeeeehaaaa!

Can ya tell I'm elated? ;o)

Besides Mrs. 4CJ, a friend's wife has it as well. Thanks for the ping!

81 posted on 02/21/2003 6:36:14 AM PST by 4CJ (Be nice to liberals, medicate them to the point of unconsciousness.)
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To: GailA

About the silver. . I know I'm probably going to be flamed, but hear me out. Back during the Y2K scare, we went to a sort of market/expo where various people were selling all kinds of Y2K supplies and fixes. I noticed the guy who was selling the colloidal silver products and machines, and who claimed to take it in serious amounts. He looked absolutely GRAY with bags under his eyes and dark circles all round his eyes. His hair was very gray and his skin was very gray (as much of it was I could see) particularly his face and neck. Then I read "Rosemary's Story" on the internet about having used colloidal silver nosedrops many years ago and having had it turn her gray (there is no cure for it). I know a lot of people claim it has done wonders for them and hasn't turned them gray; but there is absolutely no way to know where the metal is going to settle in the body. All I know is what I saw with the guy selling the products, and he definitely was abnormally gray.

I realize that when people start taking something or using (and selling) a product, it is very difficult for them to admit it even when things aren't looking too good.


82 posted on 01/05/2005 3:00:40 PM PST by Twinkie (FR HAS TO BE THERE WHEN IT'S NEEDED!! DONATE A FEW BUCKS TODAY!!)
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To: GailA
GailA: Thanks for your comments. I was fearful for my sister's life. She had rheumatoid arthritis, fibro plus other autoimmune disorders.

Out of desperation I went to the Internet and over and over found about a condition called "leaky gut syndrome". I gave her the info and told her to decide for herself if she thought it made sense.

She had liver damage from all the drugs. Her change in direction from drugs to natural therapies and diet have made a huge difference but she's still having trouble with fibro.

I like Dr. Walt Stoll's webpage.

83 posted on 02/26/2005 5:39:12 AM PST by Conservativegreatgrandma
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To: GailA; Just Kimberly
Patient Ratings Of Lyrica(Pregabalin)

FYI. Looks promising!

84 posted on 02/26/2005 12:10:50 PM PST by MamaLucci (Libs, want answers on 911? Ask Clinton why he met with Monica more than with his CIA director.)
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To: All

I am currently trying Dr. Lowe’s Metabolic Treatment for fibromyalgia and feel 50% better. Its been 8 days.
Thought I would share this, it seems to be working for me. I suffer badly from pain and fatigue.


85 posted on 05/12/2007 4:35:46 PM PDT by itsisela
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To: GailA

I have had this for many years. Some of my symptoms have been severe chest pain which feels like a heart attack. Mine seems to be under control unless I am under a great deal of stress or try to lift something that I know I should not.


86 posted on 05/12/2007 4:41:00 PM PDT by MamaB
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To: MamaB
Stress seems to make the Fibro worse for every one. I have Osteo A in several joints along with the Fibro, and it makes for a lot of pain. The bad thing is I have severe reactions to most of all the drugs they try me on. 2 celebrex tabs and my gastro intestinal track took 10 days to recover. It's not that the arthtitis drugs don't do their job, it's the horrible side effects that get me. Lyrica made my vision blur(I wear a strong RX as it is), my hands and feet swell...I have OA in my hands and they swell enough from that.

I've applied for disability because of these conditions, but am told I'm not 'bad' enough, that I can work 40 hrs a week doing data entry...I can't sit a hour without getting stiff, my hands hurt to bad to do 8 hrs of typing a day. If I can't quilt for 8 hrs a day what makes them think I could type for that long?

Be sure to do some exercising daily to keep mobile...I use Richard Simmon's Silver Foxes tape as it is not to fast for a 59 year old to do...or one who is no longer limber enough for all that gyration in the other tapes.

The more I learn about Fibro the more I find it is the cause for other things like toe and leg cramps which I get several times a day.

87 posted on 05/13/2007 5:13:05 AM PDT by GailA (Proud to admit I'm a quilt-a-holic.)
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To: GailA
I did not know about the leg and foot cramps. I thought mine were caused by my K being too low. I could not understand that though since I eat a lot of food which has K in them.

It is a very misunderstood health problem. I was in a group where some of the people were in wheelchairs. Mine is not that bad but when I have a flare up, I feel absolutely terrible.

I am taking 3 or 4 drugs to keep it under control but I still have problems. I also have costochondritis and I think that gives me more problems.

88 posted on 05/13/2007 7:37:05 AM PDT by MamaB
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To: GailA
I did not know about the leg and foot cramps. I thought mine were caused by my K being too low. I could not understand that though since I eat a lot of food which has K in them.

It is a very misunderstood health problem. I was in a group where some of the people were in wheelchairs. Mine is not that bad but when I have a flare up, I feel absolutely terrible.

I am taking 3 or 4 drugs to keep it under control but I still have problems. I also have costochondritis and I think that gives me more problems.

89 posted on 05/13/2007 7:37:10 AM PDT by MamaB
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To: MamaB; itsisela
I think they learn more over time about FMS; it is just that we have other health issues that have over lapping or masking symptoms. It took 17 months of going from doc to doc, getting told it was carpal tunnel causing the nerve damage in my hands..turns out it was OA in the C 6 & 7 disc. One doc said I needed a shrink...finally found a older arthritis doc who took less than 5 mins to tell me I had OA and FMS.

I tapped Google for FMS and leg cramps and came up with this......even my arthritis doc doesn't know about the leg/toe cramps...after all FMS effects muscles why wouldn't it cause cramps in those muscles? They won't tone through exercise...I use my tape 5-7 times a week because it keeps me mobile. I tried Calcium, potasium (sp?) and magnasium for the cramps it doesn't do much, but it can't hurt the bone strength.

I'm so sensitive to drug side effects that I can't take much for pain relief besides asprin or tylenol which only take the edge off it. The OA can't be treated because all they have on the market is gastro-intestinal destroying drugs. The musinex made ulcers in my mouth. I sleep on average 2-4 hrs a night which I know affects the FMS.

FibroFriends

FMA.org

US News fibro article

90 posted on 05/13/2007 7:44:44 PM PDT by GailA (Proud to admit I'm a quilt-a-holic.)
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To: MamaB
Well there is a new one I can add to my list...my glasses make my left eye burn along the lash line....It doesn't happen when I don't wear my glasses..and I'm extremely dependent on them.fibro

Do or did you have: childhood growing pains, FMS/MPS sinus syndrome (travelling nocturnal stuffiness), allergies, post nasal drip, swollen glands, headaches/migraine, problems getting to sleep, frequent waking, light sleep, nonrestorative sleep, night sweats, morning stiffness, fatigue, shortness of breath, painful weak grip that sometimes lets go, hypoglycemic symptoms, thyroid dysfunction, difficulty swallowing, dizziness when turn head fast, mold/yeast sensitivity, reflux esophagitis, menstrual problems, pelvic pain, PMS, fat pad over belly, nail ridges and beads/nails that curve under, difficulty getting words out you know, especially nouns and pronouns, directional disorientation, visual perception problems, short-term memory impairment, weight gain or loss, extreme sensitivity to odors, mitral valve prolapse, double vision/blurry vision/changing vision, ear aches/ringing/ itch, difficulty hearing over the phone, unexplained toothaches, rapid heart beat, fluttery heart beat/heart-attack like pain, bloating/nausea/intestinal cramps, appendicitis-like pains, carbohydrate/chocolate craving, sensitivity to heat/cold/humidity/light/pressure changes, Reynauds, visual floaters, constantly runny nose, panic attacks, confusional states, sleep apnea, thumb pain and tingling numbness, a tendency to cry easily, difficulty driving at night, weak ankles, leg cramps, groin pain, irritable bladder/bowel, sciatica, impotence, painful intercourse, mottled skin, burping, numbness, tingling, muscle twitching, hypersensitive nipples/breast pain, fibrocystic breasts, buckling knee, problems climbing stairs, free-floating anxiety, mood swings, unaccountable irritability, trouble concentrating, depression, shin-splints, FMS/MPS foot (wide in front, narrow in back with high arch), Morton's foot (longer second toe than great toe and wide web between), sensory overload, hand-writing difficulties, adrenalin surges, sore spot on top of head, problems holding arms over head, "fugue" type states when stare into space before brain can continue functioning, tight hamstrings, numbness tingling and odd sensations on outer thigh, balance problems/staggering gait, problems with electronic equipment, insomnia during full moon, energized by lightning storms, empathic sense,restless leg syndrome, body jumps before sleep, sensitivity/attractiveness to blackflies, feeling of continued movement after car stops, tilted feeling when cornering in car, pain with pressure of eyeglasses/headbands/hats, thick secretions, pain when hands are in cold water, dizziness looking at stripes and patterns, teeth grinding, inability to recognize familiar surroundings, delayed reactions to overdoing it? These can all come with FMS/MPS.

91 posted on 05/13/2007 8:05:58 PM PDT by GailA (Proud to admit I'm a quilt-a-holic.)
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To: MamaB
Check out this site's symptoms list , the chest pain condition is mentioned. I always thought my memory problems were directly related to the loss of my son..in a way it is as the FMS was triggered by it.
92 posted on 05/14/2007 4:26:07 AM PDT by GailA (Proud to admit I'm a quilt-a-holic.)
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