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To: cpforlife.org
As I understood him, he said that we are each quite different genetically now than we were at conception ... Perhaps your friend was referring to the 'genetic clock', the telomeres, one of which is lost with every cell division. Each newly constructed cell that makes up the tissues of the human organism (the form and function age beyond the totipotent and pluripotent ages) loses a link in the telomere chain when the genetic material within the cell duplicates before dividing.

When Dolly was conceived, the chromosomal data inserted into the denucleated ovum was 'aged', had used many of the telomeres leaving less for a full lifetime than if the sheep had been conceived from original male and female gametes.

Also, within the cell are mitochondrial grains which contain genetic material unique to the female's ancestry but not the 'drivers' of growth and development for the ages the conceptus goes through. The uneven timeline is the problematic issue with cloning at present, though an enzyme, Telemerase, which re-starts the clock of telomeres has been discovered. Until ALL problems are solved with higher non-human mammals, no human reproductive cloning should be legal, for starters.

I hope that helps. There is a bit more detail in the essay posted on my profile age, if anyone is interested.

92 posted on 01/31/2003 11:15:00 PM PST by MHGinTN (If you can read this, you've had life support from someone. Promote Life Support for others.)
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To: unspun; Hajman
Ping
93 posted on 01/31/2003 11:18:13 PM PST by MHGinTN (If you can read this, you've had life support from someone. Promote Life Support for others.)
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To: MHGinTN
Woa! This is seriously complicated material. I will revisit your very informative page and read slowly.

I hereby nominate MHGinTN to head the FR department of biology, genetics etc.

Now I must get an icepack, I tink I tore a telomere!

94 posted on 01/31/2003 11:41:40 PM PST by cpforlife.org
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