Even if they are not forged, usually these mean little. Many spammers have software that probes for open relays or formmail scripts that can be hijacked.
I have a couple of attempts on my site every day.
Herndon, VA is where Network solutions and AOL live. France is spam-friendly (Wannadoo.fr is one of the worst spam spigots on earth; Their abuse department is useless.) Canada has long been a troublesome source, even before spam mail, they ran telemarketing boiler room operations there.
These are just a sampling, there are hundreds more.
The IP in Herndon, VA is owned by RoadRunner (another moderately large ISP). France and Canada also have large, vocal, populations of Muslims as well as spammers. I often trace Palestinian hackers back to ISPs in Israel.
Right now, it appears to be a mystery. I think more research is needed.