"Red hats" typically go to ordinaries of particular sees. St. Louis has had cardinals in the past (Ritter and Carberry), but Rigali is still purple. Baltimore has also had cardinals, though Borders was passed over.
Denver has never had a cardinal.
Besides, I don't see why anyone would aspire to the cardinalate. Bishops are "ordained," cardinals are "created."
"To create" means to make something out of nothing.