As a LONG time Aerosmith fan, I must point out that their careers were
over.........due to excessive drug use more than anything else...........when Run DMC's rap mix of "Walk This Way" hit the airwaves. It was such a smash hit that it allowed for Aerosmith's reemergence on the rock scene. Of course, their management spent a
fortune running all of 'em through rehab......and even then they literally had to
audition to get a recording contract (their reputations had been sullied by years of drug-induced sloppy performances, etc., etc.; they had to prove themselves worthy of such significant record company investment).
I've seen interviews where Tyler and Perry will point out the release of Run DMC's remix as a true turning point in their lives as well as their careers.