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In 1914 an unconstitutional legislative 'act' was passed, prohibiting some drugs. - tpaine

Georgia had a prohibition edict in place in 1733. The Oregon Territory had prohibition in 1843. Maine had a prohibition law in 1846. In the 19th century, New Hampshire, Vermont and Michigan, among others, had prohibition laws on the books.

Yep, and except for 1733, they were all unconstitutional state laws, under the supreme Law of the Land.
--- Then, [exactly because so many states were violating the constitution, - even the 2nd amendment], -- the 14th was ratified, in order to settle the question of 'states rights'. States were told they could NOT deprive "persons of life, liberty, or property, without due process of law;".
Guns & drugs are property, prohibitions on them are NOT due process.
--- The public use of property is legally regulated under the criminal law powers granted to states. - States have NEVER been granted the power to prohibit property. [See the 9th/10th amendments]