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Facts about Smallpox
CDC (communicable disase center of US Government) ^ | October 25, 2001 | CDC

Posted on 06/22/2002 12:48:03 PM PDT by LadyDoc

What should I know about Smallpox?

Vaccination is not recommended, and the vaccine is not available to health providers or the public. In the absence of a confirmed case of smallpox anywhere in the world, there is no need to be vaccinated against smallpox. There also can be severe side effects to the smallpox vaccine, which is another reason we do not recommend vaccination. In the event of an outbreak, the CDC has clear guidelines to swiftly provide vaccine to people exposed to this disease. The vaccine is securely stored for use in the case of an outbreak. In addition, Secretary of Health and Human Services Tommy Thompson recently announced plans to accelerate production of a new smallpox vaccine.

Are we expecting a smallpox attack?

We are not expecting a smallpox attack, but the recent events that include the use of biological agents as weapons have heightened our awareness of the possibility of such an attack.

Is there an immediate smallpox threat?

At this time we have no information that suggests an imminent smallpox threat.

If I am concerned about a smallpox attack, can I go to my doctor and request the smallpox vaccine?

The last naturally acquired case of smallpox occurred in 1977. The last cases of smallpox, from laboratory exposure, occurred in 1978. In the United States, routine vaccination against smallpox ended in 1972. Since the vaccine is no longer recommended, the vaccine is not available. The CDC maintains an emergency supply of vaccine that can be released if necessary, since post-exposure vaccination is effective.

Are there plans to manufacture more vaccine in case of a bioterrorism attack using smallpox?

Yes. In 2000, CDC awarded a contract to a vaccine manufacturer to produce additional doses of smallpox vaccine.

If someone comes in contact with smallpox, how long does it take to show symptoms?

The incubation period is about 12 days (range: 7 to 17 days) following exposure. Initial symptoms include high fever, fatigue, and head and back aches. A characteristic rash, most prominent on the face, arms, and legs, follows in 2-3 days. The rash starts with flat red lesions that evolve at the same rate. Lesions become pus-filled after a few days and then begin to crust early in the second week. Scabs develop and then separate and fall off after about 3-4 weeks.

Is smallpox fatal?

The majority of patients with smallpox recover, but death may occur in up to 30% of cases.

How is smallpox spread?

In the majority of cases, smallpox is spread from one person to another by infected saliva droplets that expose a susceptible person having face-to-face contact with the ill person. People with smallpox are most infectious during the first week of illness, because that is when the largest amount of virus is present in saliva. However, some risk of transmission lasts until all scabs have fallen off.

Contaminated clothing or bed linen could also spread the virus. Special precautions need to be taken to ensure that all bedding and clothing of patients are cleaned appropriately with bleach and hot water. Disinfectants such as bleach and quaternary ammonia can be used for cleaning contaminated surfaces.

If someone is exposed to smallpox, is it too late to get a vaccination?

If the vaccine is given within 4 days after exposure to smallpox, it can lessen the severity of illness or even prevent it.

If people got the vaccination in the past when it was used routinely, will they be immune?

Not necessarily. Routine vaccination against smallpox ended in 1972. The level of immunity, if any, among persons who were vaccinated before 1972 is uncertain; therefore, these persons are assumed to be susceptible. For those who were vaccinated, it is not known how long immunity lasts. Most estimates suggest immunity from the vaccination lasts 3 to 5 years. This means that nearly the entire U.S. population has partial immunity at best. Immunity can be boosted effectively with a single revaccination. Prior infection with the disease grants lifelong immunity.


TOPICS: News/Current Events
KEYWORDS: bioterror; biowarfare; opic; smallpox; vaccines
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There have been several posts on smallpox, and about whether or not to get the vaccine. The weblink above is to the CDC site and has a lot of answers.

There are links at the start of the article about other bioterror diseases also.

1 posted on 06/22/2002 12:48:03 PM PDT by LadyDoc
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To: LadyDoc
I think that, after a little translation from the CDC bureaucrat-speak, here is what this statement really says:

"Folks, we do not have enough vaccine for even a small fraction of the population of the U.S., let alone our allies. However, if we just came out and admitted that, there would be massive public dissatisfaction- the image of the CDC would be harmed. Can't have that. So just go back to sleep, and we'll all agree to pretend that everything is under control".

2 posted on 06/22/2002 12:52:58 PM PDT by RANGERAIRBORNE
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To: LadyDoc
I appreciate your posting this. I'd also like you to respond to the following, please:

1. What is the perceived rate of morbidity/mortality from vaccination of the entire US population?

2. How viable is the vaccine which has been in storage since the 70's? In other words, what is the expected efficacy of a vaccine of this age?

3. We know the Soviets were working to shorten the incubation period of smallpox infection (See Ken Alibek's book). IF they were able to successfully accomplish this, wouldn't the current plan to quarrantine and then vaccinate those in an outbreak area be mute?

4. Is there a chance that the Soviets were able to genetically mutate the virus so that currently available vaccines may not be effective against this kind of outbreak?

Thanks.
3 posted on 06/22/2002 1:02:11 PM PDT by Endeavor
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To: Endeavor
Make that "moot" rather than "mute" although the latter may apply as well.
4 posted on 06/22/2002 1:04:11 PM PDT by Endeavor
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To: LadyDoc
There are some people with other ailments or diseases that should not get this smallpox vaccination. Called, contraindictions. Exema is one. What else aren't they warning about?
5 posted on 06/22/2002 1:40:13 PM PDT by poetknowit
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To: LadyDoc; RANGERAIRBORNE
I have been vaccinated a total of five times in my life, the last in 1971. I never had any material adverse reaction--usual localized redness etc. For one thing, I assume, maybe incorrect, that I am more likely to be immune than the average person. I also assume, that if I did get vaccinated today, I would be unlikely to have any of these material life-threatening reactions (I am not in one of the threatened immunine disorder groups).

That said, it seems to me that in a free country, I should be able to walk up to a health care provider and buy a vaccination tomorrow morning which I would like to do. I am not even so sure Rangerairborne is correct--it is in my mind explicable that CDC has enough vaccine but is not letting it out into the marketplace because they think they know better.

Nothing direct I can do about it in the immediate future. But I am not going to vote for George Bush again either.

6 posted on 06/22/2002 2:02:34 PM PDT by David
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To: *Bio_warfare
*Index Bump
7 posted on 06/22/2002 2:04:15 PM PDT by Fish out of Water
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To: RANGERAIRBORNE
You got it right. You will note from the CDC double-talk that the incubation period is 7-17 days. Then they reassure us that if given within four days of exposure the vaccination MIGHT help. Now although I was mostly educated in public california schools, I think 7 is greater than 4; that is by the time you know the disease is out there, it's too late. One puff of this stuff in an inhaler in a stadium would kill 10 to 20 thousand people in 2 weeks. And the ONLY thing you could do to stop it is vaccinate the population before the bio-attack. And that's just the primary cases.

Apparently the CDC is more than happy to sacrifice a few hundred thousand people rather than let the people make up their own minds about whether they should be vaccinated. I doubt strongly that the complications from the vaccine would be anything more than a few hundred cases of disease in those on chemotherapy and with end-stage Aids.

Infectious disease specialists say that smallpox outbreaks from a lab accident or a monkeypox mutation could be easily contained. A more pertinent question would be what about containing multiple attacks in large venues like stadiums or convention centers simultaneously? The death toll would be quite high.

Do the bad guys have smallpox? Of course they do. Anything the Russians or Chinese have, the terrorists have. After all, it was and is Russia and China who continue to support these countries like Syria and Iraq.

Personally, I will take the vaccine if it becomes available and so will my family. I, at least, have partial immunity; my kids don't.

Any freeper out there know what kinds of problems occur with the smallpox vaaccine and how frequent they are? Amazing how the government and CDC carefully omit this most vital of information from their propaganda.

8 posted on 06/22/2002 2:04:17 PM PDT by baxter999
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To: RANGERAIRBORNE
After this article was published, they found 70 million doses of vaccine. Since you can dilute it to one third a dose and still have it work, there is now enough vaccine for all.
9 posted on 06/22/2002 2:07:23 PM PDT by LadyDoc
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To: David
Regarding the amount of vaccine, Ranger is correct. In a toxic chemical training course I took a few weeks ago (June 1, 2002) taught by an expert in the Field (John Urbanetti), he mentioned that there is about a 2 year period before there would be enough vaccine for the country - even if you split the old stuff and even if it worked. And even if we could talk France into releasing it to us, because in one of those incredibly stupid government maneuvers like buying military uniforms from our enemy China, that's where the government is getting the vaccine made. Even though it could easily be done in the US.

But then that would make sense and benefit our economy rather than Euroworld.

10 posted on 06/22/2002 2:11:55 PM PDT by baxter999
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To: LadyDoc
Here is a fascinating and horrifying New Yorker article on Small Pox: The Demon in the Freezer.

Required reading, IMHO.

11 posted on 06/22/2002 2:17:53 PM PDT by r9etb
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To: Endeavor; poetknowit; David
The mortality of vaccinating the population is unknown. You see, we didn't have HIV in the good old days. And we had a lot fewer people on chemotherapy in the 1970's than we do now. One reason the army checks HIV is that they almost lost a soldier giving it to him, since he was HIV positive and they didn't have a test for HIV back then. Ditto for chemotherapy: The infection might kill them. (For example, chicken pox can kill cancer patients with poor immune systems).

On the other hand, we now have anti viral medication, whereas in the 1970's we only had a small amount of anti serum

Poetknowit is right in pointing out that the vaccine, which causes a sore, can spread to others. So even if we don't vaccinate you, you could catch generalized vaccinia from other people. And remember, most people with HIV don't know they have it...

Also, as Poetknowit points out, vaccinia can be spread to people with ecsema. When you have ecsema, you have lots of cracks in the skin. So even if you are not vaccinated, you could catch it by living with or near someone who has an active vaccine sore, if some of the virus got into your skin. Instead of one sore, you might have dozens of vaccinia sores and be very sick.

This is why David, who understandably wants to get the vaccine, is wrong. He might spread it to another person by accident.

12 posted on 06/22/2002 2:18:36 PM PDT by LadyDoc
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To: LadyDoc
CDC speak many weasel-words.
13 posted on 06/22/2002 2:19:48 PM PDT by john in missouri
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To: r9etb
Re: The demon in the freezer. Thanks. I missed that one.
14 posted on 06/22/2002 2:21:53 PM PDT by LadyDoc
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To: RANGERAIRBORNE
Actually, if existing supplies were to be diluted 1:10 (still fully effective, NEJM 2002), we could vaccinate everyone.

I think the decision to forbid vaccine on request is irresponsible. If vaccine were available to me (and it may be available to me soon, as a probable first responder to a smallpox emergency), I would take it, and use the material from the blister fluid to inoculate my family.

The resistance to widespread vaccination by the federales has two important roots:

1) The "eradication" of smallpox is felt by the involved parties to be the leading Public Health triumph of the century just past. The fact that smallpox was "eradicated" in the sense that war was eradicated by the Kellog-Briand treaty in 1928 is lost on these people.

2) The government is deathly afraid of liability for side effects, especially from fatalities among those with undiagnosed immune deficiency diseases.

In any event, there is enough (diluted) vaccine for everyone-the refusal to allow its use is fundamentally political.

15 posted on 06/22/2002 2:31:59 PM PDT by Jim Noble
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To: r9etb
From the USAMRIID's (US Army medical research institute of infectious disease) Medical management of biological casualties handbook, Fourth edition, February 2001, page 87 comes the following:

"Side effects [of the vaccine]include low-grade fever and axillary lymphadenopathy. The attendant erythema and induration of the vaccination vesicle is frequently misdiagnosed as a bacterial superinfection. More severe first-time vaccine reactions include secondary inoculation of the virus to other sites such as the face, eyelid, or other persons (~6/10,000 vaccinations), and generalized vaccinia, which is a systemic spread of the virus to produce mucocutaneous lesions away from the primary vaccination site (~3/10,000 vaccinations).

Vaccination is contraindicated in the following conditions: immunosupression, HIV infection, history or evidence of eczema, or current household, sexual, or other close physical contact with person(s) possessing one of these conditions. In addition, vaccination should not be performed during pregnancy, Despite these caveats, most authorities state that, with the exception of significant impairment of systemic immunity, there are no absolute contraindications to post-exposure vaccination of a person who experiences bona fide exposure to variola[smallpox]. However, concomitant VIG [smallpox immune globulin] administration is recommended for pregnant and eczematous persons in such circumstances."

Although Aids is a new disease, eczema and pregnancy are not new. And the vaccine was quite safe.

Of course, if the massive stockpiles of smallpox that Russia developed within months of signing the biological warfare treaty include modified strains, then even new vaccine would be useless.

I note from the book that June 30, 2002 is the date when all smallpox is set to be destroyed in the US, thus rendering us impotent in preparing for any new problems with smallpox. Is that why the government is pushing all of this "don't worry" propaganda, so that we won't squeak when our ability to do research on smallpox ends?

Any freepers in the CDC or current military who know whether this is still the case?

If the vaccine is available, I and my family will take it, and I will advise my patients to seriously consider taking it themselves.

16 posted on 06/22/2002 2:46:59 PM PDT by baxter999
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To: baxter999
Let me correct one thing I said in my last blurb. The biological treaty was signed in the 1970's. The WHO declared smallpox extinct in the wild in 1980. Within 6 months, Russia had 3 full-time factories producing smallpox for weapons. The current status of Russia's (and other countries) production of smallpox is unknown. Who has this stuff is also unknown, but Russia has sponsored terrorism and terrorist states like Syria, Libya and Iraq for years. They probably have it.

Again, I'll take the vaccine and the government should allow its availability so that physicians and patients can make up their own minds. But in the new United Socialist States of America we apparently will not have that freedom.

17 posted on 06/22/2002 2:54:57 PM PDT by baxter999
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To: baxter999
The Feds maintain a number of "National Pharmaceutical Stockpliles" strategically positioned around the country. In case of an actual or suspected bioterrorist attack, and when requested by a State health department, these shipments (vaccines, medical supplies, antibiotics, etc) can be delivered anywhere in the country within 12 hours. Following the 9/11 attack, New York City was supplied in 7 hours.

The focus needs to be on RAPID detection of unusual disease or disease patterns, before the cases spread widely. State and local health departments have been ramping up their surveillance and reaction capabilities, thanks to federal funding ( it's about time our tax dollars went to something important and Constitutional).

18 posted on 06/22/2002 2:59:04 PM PDT by AngrySpud
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To: baxter999
P.S. ... I agree that it should be available to those who want it and who accept the (small) risk.
19 posted on 06/22/2002 3:01:02 PM PDT by AngrySpud
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To: David
You lucky guy. You're totally immunized...the rest of us are sitting ducks... you must have served our nation in the US military...thanks for serving...
20 posted on 06/22/2002 3:03:22 PM PDT by bonesmccoy
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