Sure, for one static target. Those five rounds go away very quickly if you've ever been through a shoot house drill engaging multiple targets with recovery of missed shots and a failure-to-stop head-shot or two. Of course, if you're a lot better with a speed loader than I am, the point is moot. :-)
That SA 45 Colt loads as fast as I can work with holding 6 bullets in one hand and trying to work the cylinder and the hammer and the shell ejector with the other. My times aren't much good even though I don't hardly ever miss a shot. Easy to see the advantage of carrying two pistols like Wild Bill. Or six pistols like Blackbeard the Pirate, but his brand of coffee isn't for most people.