I've thought of doing a spreadsheet of costs/benefits, but it would take a little thought. For example, the cost of drug enforcement includes but is not limited to: bloated police forces, extra jails, time lost from work by users in the legal system, courts, juries, lawyers, the inflated cost of drugs, deaths due to lifesaving drugs held from the market, the cost of the FDA, many etcs.
And then on the opposite side are the very real costs of drug addiction, work injuries, lost productivity, etc. I suspect, however, that the true cost of the WOD dwarfs the negative drug costs.
Difficult to tell, isn't it? In my parent's day (Great Depression kids) and their parents day, no problem. Their could have been offered all the drugs they wanted for free and they would not have taken them. A half a century of liberal mind rot latter, I don't know how bad it might get if the more serious drugs were legal.