Doesn't sound to me like a nuke would be effective. About the only thing you could do would be to evacuate the East Coast cities asap.
However, it also doesn't sound plausible to me that the Cumbre Vieja event could be triggered by terrorist activity. This ridge is TWELVE MILES long, and it really seems to require widespread volcanic activity coming from below. This is the kind of event that really seems to require some major cooking.
Now if al Qaeda had a hundred nukes at their disposal, maybe. But if they did have a hundred nukes to blow, it would seem to be far simpler and surer just to plant 'em in a bunch of US cities.
Will the mega tsunami happen? By all accounts, yes. It's going to happen someday, and quite possibly during the next couple hundred years. We came breathtakingly close in 1949, when this half of the island slid for a dozen feet or so -- and then stopped.
But when it does finally happen, my personal opinion is that it'll be triggered by large-scale natural events, not by manmade activity.
Just my 2c on the basis of a little bit of reading. YMMV.