That's the one. Who were the most prominent southern politicians who worked for and advocated "secession" of the southern states in the weeks and months before the southern states actually "seceded" from the Union?
Perhaps you should read a little history. As I have noted previously, however, "your question is largely irrelevant. It is the language of the written Constitution that is of critical importance, not the supposed competence [or prominence] of politicians - no matter how much you may prefer the words of politicians to the words of the Constitution..."
Or would you have us believe that the right to keep and bear arms, for example, is somehow dependent upon the 'prominence' of "politicians who worked for and advocated" that right? Hmm?
;>)