[Nebullis]

No, the speedometer is set for the genes. This research addresses what happens between genes and morphology, behavior, cognition, or other final expression from the genes. And how that can differ between different organs. Still, the information for those dynamic patterns is located in the genes. But a small change in a critical control region, can affect the expression of hundreds of genes. Many of the sequences involved in this type of control are not located in the traditional protein-coding regions of the genome, but lie around them, in "junk" regions.

[Diamond]

Thanks for the explanation. This is fascinating, complicated stuff.

Cordially,

[edsheppa]

What is the level of understanding for the divergence between change in genome vs. expression? I dimly recall reading that phosphorylation has something to do with it. Is this thought to be a primary effect? What's the mechanism (if you can briefly describe it is medium-sized words)? How do identical DNA sequences end up differently affected? Or do they?