Autonomy: from Autos meaning self + nomos rule
lit. self-rule
To be ruled by self is to be not under the rule of God and therefore outside his kingdom. It is in fact the state of sin or separation from God. When one repents, they humble themselves from self-rule and place themselves under the authority or rule of God.
One cannot be fully devoted to God and deny His authority in their professional life - even in the civil magistrate.