Probably so. Any cities or villages along ancient coastlines would have been inundated by the rising seas.
Remember, sea levels were several hundred feet lower during the last Ice Age.
Most people then, like now, lived near the sea, especially near river deltas and sites where rivers and streams emptied into the seas.
300-500 feet. Most people accept 400 feet, as a rule of thumb.
Massive tidal waves of up to 2 km in height would have pulverized most everything in advance of the rising waters from the Antarctic melt off.
Simply assume Antarctica melted or softened on the edges, and then released suddenly. Just before the current interglacial, this ice was up to 4 miles deep.
This would happen at the end of every major glaciation and would have destroyed all coastal civilizations on every continent. Remember the total pulverization of material goods that occured with the World Trade Center collapse - now, imagine that 6 to 10 times as tall and covering a wide area. About the only places anything or anybody could have survived would be in the Rockies, the Himalayas, or in the middle of the Sahara (which was green and lush in those days).
I think fish, rather than roast Mastodon, formed the most important source of protein in ancient human diets. Fish is easy to catch with primitive equipment and can be eaten raw or with minimal cooking.