America can't be true to its basic principle of equality for all people and at the same time take sides in tribal wars, or become the world's policeman whether or not the rest of the world likes it or not.
Both courses require extensive military-industrial complexes, equally extensive government and foreign policy infrastructures supported by massive taxes, and centralized decision-making and command infrastructures which completely override any regional or local considerations. Having worldwide plans and courses of action for anything is much closer to Stalinism than for any concept of universal freedom.
As far as Osama himself, his initial politization was during the Afghan jihad against the Soviets. Many of his early comrades were from Egypt, where Anwar Sadat's and Mubarak's governments expelled them from to get rid of a potentially deadly opposition in their midst.
It was after seeing so many of these people being used as cannon fodder by America in its proxy war against the Soviet Union, that Bin Ladin's own beliefs started becoming more radical. America's complete abandonment of the Afghan muj and the country, after the Soviets withdrew in 1989, combined with the American Persian Gulf intervention in 1990 to perserve its oil supply, caused him to conclude there is a hopeless tilt towards the Zionists and away from even people who lost millions fighting our battles.