[PrairieFire]

A strong argument can be made that OOBuck is the best load for protection. Think about it. Each shell contains 9 projectiles each of which are 33 cal. If you shoot from 10 to 15 feet away (which is likely in your home), the pattern should be sufficiently close to do real damage. The muzzle velocity is also very good.

I would also recommend that you have only one type of load in the shotgun at any given time. That way you will always know what is coming out of the business end next.

Just for what it's worth.

[Shooter 2.5]

A good defensive course can teach you to change out ammo in a split second. There isn’t a reason not to know which type of shell is going to be fired.