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Trial for autoimmune disease treatment urgently halted after multiple participants die
DailyMail US ^ | 09/01/26 | Emily Sterne

Posted on 09/01/2026 7:38:52 PM PDT by doc maverick

“Trials testing an experimental medication have been urgently halted following the death of multiple participants. Swiss drug manufacturer Novartis said Tuesday that it paused eight clinical trials of the cell therapy rap-cel after the deaths of three patients. The halt began on August 24 after Novartis was notified of three cases of a rare but life-threatening allergic reaction called immune effector cell-associated hemophagocytic syndrome (IEC-HS), the company spokesperson said.”

(Excerpt) Read more at dailymail.com ...


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“Immune effector cell (IEC) therapy can result in hemophagocytic lymphohistiocytosis (HLH)-like events, which are now understood as separate entities. Rare and fatal, HLH is characterized by abnormal activation of natural killer (NK) cells, macrophages, and cytotoxic T-lymphocytes; this leads to supraphysiologic production of cytokines and immune-mediated organ system damage.” Messing with the immune system by injection or medication can cause your organs to “self destruct.” At least we’re hearing about it. Who knows what kind of “test trials” were done on covid vaccines…..or what really happened with them. I know a ten year old girl lost the use of her legs….but Fauci probably kniws.
1 posted on 09/01/2026 7:38:52 PM PDT by doc maverick
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To: doc maverick

That wouldn’t stop Saint Fauci the Divine!


2 posted on 09/01/2026 7:46:53 PM PDT by null and void (Iran Pres Masoud Pezeshkian: “Common sense is a good thing ... Common sense is really a good thing.")
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To: doc maverick

If you try to make a tumor vaccine using an immune modulator combined with tumor cells, the immune response generated may also be directed aagainst healthy tissue. Tumor antigens may have a great degree of commonality with healthy tissue.Looks like what happened here. Good luck trying to isolate or harvest unique tumor antigens.


3 posted on 09/01/2026 7:51:44 PM PDT by allendale
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To: doc maverick

“The halt began on August 24 after Novartis was notified of three cases of a rare but life-threatening allergic reaction called immune effector cell-associated hemophagocytic syndrome”

Well, duhhh, anyone with half a brain would know this type of drug would lead to immune effector cell-associated hemophagocytic syndrome. I learned that in Kindergarten.


4 posted on 09/01/2026 7:55:29 PM PDT by BobL (Trusting one's doctor is the #1 health mistake one can make.)
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To: doc maverick

“The halt began on August 24 after Novartis was notified of three cases of a rare but life-threatening allergic reaction called immune effector cell-associated hemophagocytic syndrome”

Well, duhhh, anyone with half a brain would know this type of drug would lead to immune effector cell-associated hemophagocytic syndrome. I learned that in Kindergarten.


5 posted on 09/01/2026 7:55:32 PM PDT by BobL (Trusting one's doctor is the #1 health mistake one can make.)
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To: doc maverick

Safe and effective. Give a double dose to Hannity


6 posted on 09/01/2026 8:00:24 PM PDT by Wilderness Conservative (Death to the DEATH TO AMERICA, Democrats.)
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To: null and void

Trust the science
Two weeks to flatten the curve
Guess these guys are observing the 6’ distance rule


7 posted on 09/01/2026 8:03:53 PM PDT by Keyhopper (Indians had bad immigration laws)
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To: BobL

The 3 cases were all iFATAL.
These medical researchers should have known better, but all they concentrate on now in medical schools is woke horse shit. I’ve noticed that some new physicians I’ve been around can’t even diagnose pneumonia using a stethoscope!


8 posted on 09/01/2026 8:08:32 PM PDT by doc maverick
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To: Keyhopper

The three ex-patients certainly are.


9 posted on 09/01/2026 8:08:54 PM PDT by decal (They won't stop, so they'll have to be stopped)
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To: doc maverick

Just list death as a possible side effect.


10 posted on 09/01/2026 8:17:46 PM PDT by GMMC0987
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To: GMMC0987

Shows that it is working.


11 posted on 09/01/2026 8:31:16 PM PDT by Deaf Smith (When a Texan takes his chances, chances will be taken that's for sure.)
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To: doc maverick

Too bad that such scrutiny wasn’t in place for the ‘clot-shot’ clinical trials!

Oh wait...You mean a procedure WAS in place, only ignored???


12 posted on 09/01/2026 8:52:44 PM PDT by Oscar in Batangas (An Honors Graduate from the Don Rickles School of Personal Verbal Intercourse)
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To: Oscar in Batangas

I wonder what Pfizer would have done in this position?


13 posted on 09/01/2026 10:02:28 PM PDT by Tymesup
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To: doc maverick
three cases of a rare but life-threatening fatal allergic reaction

Thanks for the post, I know some one who has been bed-ridden by a similar treatment/reaction. I don't know if it's the same trial.

14 posted on 09/02/2026 12:10:40 AM PDT by Mr Radical (In times of universal deceit, telling the truth is a revolutionary act.)
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To: Deaf Smith

“Effective”. Depending on the goal.


15 posted on 09/02/2026 12:26:34 AM PDT by MayflowerMadam (In the end, we will remember not the words of our enemies, but the silence of our friends.)
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To: allendale

It was a trial to treat auto-immune diseases. They had engineered Car-T cells to attack the “rouge” immune cells which were attacking normal tissue. Some of the diseases in the studies were lupus,rheumatoid arthritis,vasculitis. Car-T cells therapy can cause too many cytokines to be released. It is a well known side effect.
Novartis is continuing to try Car-T therapy versus cancer.

Not sure it is a good idea to use engineered immune cells to attack other immune cells. Like civil war in the immune system. The immune system is an amazingly constructed and functional entity, with lots of feedback loops. So upsetting its balance in an already “rogue” immune condition can probably cause devastating unforeseen results.

Of course the next step is to demand everyone get this therapy. Or else.


16 posted on 09/02/2026 5:18:38 AM PDT by Getready (Wisdom is more valuable than gold and harder to find.)
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To: doc maverick

Thanks for posting this. I’m “filing” it away for future reference….


17 posted on 09/02/2026 6:10:58 AM PDT by telescope115 (Ad Astra, Ad Deum…)
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To: null and void

“That wouldn’t stop Saint Fauci the Divine!”

His head should be served on a plate.


18 posted on 09/02/2026 6:16:37 AM PDT by bk1000 (Banned from Breitbart)
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To: doc maverick
I live very close to Harvard Medical School (a huge force in medical research). Over the last few years I,being retired,have made very good money participating in research studies there.I guess I've always known that death is a possibility. But I've always had the attitude “live fast,die young and leave a good looking corpse” so that's not a problem.
19 posted on 09/02/2026 6:47:02 AM PDT by Gay State Conservative (Import The Third World,Become The Third World)
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To: bk1000

Multiple multiple mRNA booster shots should suffice...


20 posted on 09/02/2026 7:12:50 AM PDT by null and void (Iran Pres Masoud Pezeshkian: “Common sense is a good thing ... Common sense is really a good thing.")
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