LOL!! How has that worked for alcohol? People still become alcoholics, people still die from alcohol-induced diseases, people still contract alcohol-induced dementia, psychosis, and other mental disorders, they drive while intoxicated, kill themselves and other people while driving drunk, commit crimes under the influence, and commit crimes to get money to buy alcohol and drugs. So much for ensuring safety.
Drinking is permissible and prohibition did not stop it. You’re not going to stop people taking drugs prohibition either. You’re best chance is harm reduction, to teach people the limits of how much to use.
We’ve already tried prohibition and at least two Presidents became rich because of it.