I agree that it's difficult for them, when not impossible. The user has to really want to quit, treatment has to be available, and a change of, ahem, associates is a good thing. When I read of Hollywood show people or musicians going clean, I'm skeptical.
These drugs alter brain chemistry and things don’t return to “normal” even during periods of “sobriety”. Sad when a teen starts down this road after receiving pain meds after an accident or dental surgery .
Or when their "friends" talk them in trying. Peer pressure is a major force in our younger citizens.
What about Ozempic? It seems to stop any kind of addiction.