Maternal syphilis rates increased across all racial and ethnic groups each year from 2016 to 2022. The largest increase, at 783%, occurred among American Indian and Alaska Native mothers. They also had the highest infection rate of 1,410.5 cases per 100,000 births in 2022.
The maternal syphilis rate among white non-Hispanic mothers rose 315% from 2016 to 2022, while Hispanic mothers experienced an increase of 243%. The rate among Black mothers increased by 149% during the same time frame, compared with a 92% increase among Asian mothers. Asian mothers had the lowest maternal syphilis rate of any racial or ethnic group in 2022, at 73.3 per 100,000.
The increase rates are meaningless without knowing the baseline rates.