“Isn’t DeSantis a big pro-lifer and didn’t he insist on enforcing abortion laws?”
If your state is culturally pro-life then you can win as a pro-life candidate.
Pennsylvania showed that if you push pro-life in a state which is not culturally pro-life, then you lose. Politics is downstream from culture.
A State with a Tranny Health Secretary is probably not going to be a bastion of Pro-Life.