[Wallace T.]

With virtually no exceptions, state chartered banks are regulated by either the Fed or the FDIC. State banks are by and large subject to the same regulations as national banks. Most proposed regulations are issued jointly by the OCC (national banks), the Fed (state banks that are Fed members) and the FDIC (state banks that are not Fed members).

While the largest U.S. banks are largely National charters, there are several banks with more than $100 billion in assets that have state charters. In some states, e.g. New York, the state banking department is more aggressive and anti-business than their Federal counterparts.

SEC regulations affect publicly traded banks only.

[MrKatykelly]

Agreed. Still prefer State Banks.