Pence has a record of care with and around women — during work, meetings, travel, campaigning. Pence is a Christian with a kind and caring core, I think.
Maybe he treats her like a confused sister, gently enlightening her about realities, being mildly amused by her rants.
Would be seen as talking down to her and condescending.
Pence’s self depreciating chuckle contrasted with Heels Up’s freakish, nervous cackle.