[T. P. Pole]

immune systems are very much weakened when confined

I was thinking the folks going out are getting micro-exposures and are building defenses, when those that are staying in have virgin immune systems and need a smaller viral load to go over the edge.

[jacknhoo]

These guys explain the immunity drop from confinement pretty well:

Perspectives on the Pandemic | The Bakersfield Doctors | Episode 6

https://m.youtube.com/watch?v=3f0VRtY9oTs

[miserare]

That’s very likely.