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Looking at the whole of this, I agree with the NIH recommendation while the interpretation of this recommendation by the press is perfectly awful and inside out of what they are saying.
Zpac (azithromycin) is the problem NIH is highlighting. It has some profound risks that in mass usage equal increased side-effect damage.
The core misinformation campaign is all about misunderstanding what Hydroxychloroquine does, how it impacts the viral reproduction process because frankly this is too deep for our American press. Takes like 5 minutes to get, and it would help Trump in their minds.. so who wants to know.
Once you get the fact that what the treatment is really about is delivering Zinc to disrupt the Viral RNA reproduction factories, then we also see that this Hydroxychloroquine is not the only game in town. Its still by wide margins the “best” game because so much is already known about it, in spite of the presses campaign of misinformation. 70 years of experience has left an amazing array of interaction data. What it doesn’t provide is a regime for dosing to support Zinc.
In a perfect world, we would have years to study this but it isn’t so. So, Dr’s have been prescribing Hydroxychloroquine as it has been for years and thats that.. there is a limit to the amount of zinc you can “safely” take in a day, and they have been prescribing that. When in doubt, Dr’s use the max and hope. You might be able to get away with half this amount, but there isn’t any data to support where the line of diminishing returns really should be placed, but if the effective dose is lower for each, then the combo is even safer.
But, the use of Hydroxychloroquine and Zpac for patients who are already in acute hypoxic distress is STUCK ON STUPID. It is how regulators have framed the usage to limit its application when the most effective time is within a day of first symptom onset. This is the hardest time to actually get Hydroxychloroquine in places like New York. And, there will be a butcher’s bill to pay for this insane government over-reach.
As a prophylactic rather than an acute treatment in the first days of COVID infection, Zinc becomes a problem as it drives out trace elements, especially Copper and you need to supplement at higher than RDA to stave of predictable ill effects. For most, the smarter course is to simply set in a reactive rather than proactive stance.
That said, Hydroxychloroquine is not the only game in town. It turns out that other compounds have Zinc ionophore properties. The cheap and widely available nutritional supplement called Quercetin is one of these. Its not Hydroxychloroquine but step back and you see that it carries a similar benefit patina being anti-inflamatory and immune system support. What it doesn’t carry is all of the glorious side-effect data that we have on Hydroxychloroquine. But, there are definite issues with many antibiotics and anything that is transformed by the liver into the “effective compound” or removed from the system by the liver. This is probably something shared by Hydroxychloroquine and why antibiotics are not necessarily wise unless you are fighting a secondary infection which justifies the additional risks and side-effects.