The Wusan triad is Fever, Cough and Shortness of Breath. It is now considered diagnostic of COVID-19 infection by the New York City Board of Health. If a patient has Fever and Cough, then the this therapeutic regimen should start before the third point of the triad ,Shortness of Breath, is reached. By then the lungs have already been compromised and the clinical outcome is in doubt. People are concerned that the quinolones and Zithromax prolong the QT interval on EKG and this may lead to serious or fatal arrhythmias. Many therapeutic agents prolong the QT interval. However if a person develops a pneumonia the right side pressures of the heart increase rapidly and while myocardial tissue itself is not a direct target of the virus, the increased strain on the heart due to hypoxemia and increased pressures can in itself lead to arrhythmias.
Quinolones and Zithromax may or may not work. However as of now its the best physicians can offer to patients ill with COVID-19. RNA viruses are bad actors and developing a vaccine is difficult. However until an effective and safe vaccine is developed, this virus will continue to devastate humans and their culture.
BTW believe data out of China at your own risk.
I disagree. Review his presentation on [Youtube] and the accompanying [PDF].
"BTW believe data out of China at your own risk."
If you mean in total cases to deaths, fine. If you mean per Prof. Raoult?
"Raoult is ranked #1 expert in the world for infectious disease." - wikipedia
Raoult ran the trial in France with a French cohort (that included repatriates).
Hydroxychloroquine and Azithromycin as a treatment of COVID‐19: results of an open‐label non‐randomized clinical trial. [PDF]Patients and methods
French Confirmed COVID-19 patients were included in a single arm protocol from early March to March 16th, to receive 600mg of hydroxychloroquine daily and their viral load in nasopharyngeal swabs was tested daily in a hospital setting.
Depending on their clinical presentation, azithromycin was added to the treatment. Untreated patients from another center and cases refusing the protocol were included as negative controls. Presence and absence of virus at Day6-post inclusion was considered the end point.
Results
Six patients were asymptomatic, 22 had upper respiratory tract infection symptoms and eight had lower respiratory tract infection symptoms. Twenty cases were treated in this study and showed a significant reduction of the viral carriage at D6-post inclusion compared to controls, and much lower average carrying duration than reported of untreated patients in the literature.
Azithromycin added to hydroxychloroquine was significantly more efficient for virus elimination.
Conclusion
Despite its small sample size our survey shows that hydroxychloroquine treatment is significantly associated with viral load reduction/disappearance in COVID-19 patients and its effect is reinforced by azithromycin.
No one, not Prof. Raoult, nor I, nor President Trump, is touting PQL+AZT as a cure, it's a treatment.
A treatment to greatly reduce the viral load of COVID-19 in affected patients.
A treatment that was so successful that 5 days after publishing the preliminary positive results (see above), the French Health Ministry, CNRS, CPP (Comités de Protection des Personnes), and Raoult's own INSERM group opened the trial.
I hope I don't have to tell you how important that is, when you open a trial that isn't even a month old. Impressive enough that 10,000 PQL+AZT units will begin to be distributed to COVID-19 patients in New York this Tuesday.
Informative. Thanx.
You sound like someone with medical education/experience. Can you please address HOW an antibiotic affects a virus? I understand the hydroxycholoquine is an ionophore and also (somehow) counteracts the virus’ action re: reduction of iron transport via heme. But I do not comprehend how an antibiotic can affect a virus even after being capable of penetrating it.
I have asked this before, with no response. Professionals only, please. This question is driving me crazy.
ANOTHER protocol that is NOT approved by FDA but it is curing me. Effin bureaucrats can suck it.