If by the Constitution then only an amendment can change it's status.
Unfortunately, the Constitution does not COMMAND the creation of a Federal District.
It PERMITS such a creation, and the mechanism is cession by states (MD and VA, in this case), followed by acceptance by Congress.
A better idea would be for Wyoming and Utah to cede a ten mile square to the United States, and have Congress accept it as the New District of Columbia, give the mess on the Potomac back to Maryland, and call it a day.