So you side with fedgov pi**ing on the Tenth Amendment.
While I agree that drug laws are unconstitutional and that the drug war is destructive at many levels, this man made his living sending people to jail for what he seeks to do now, and for that I would support prosecuting him so long as the law remains on the federal books (although I do wish for it to be removed).
I have mixed thoughts, while fighting a local push (putsch) for recreational marijuana stores in my town in MA. MA passed a legalization statewide ballot measure 2 years ago, which allows towns to outright ban the stores. Legalization is one thing; commercialization is quite another. I’m a proud nimbyist on this topic, and yes, there are federal considerations.