Not in modern times, and such would be unlikely to ever happen. If it did, it would be a sweep or near-sweep of the Electoral College.
I need to see real numbers from the French electoral commission before I can really call it though. Those numbers look so fishy.
Also the regional braekdown will be one worth seeing. Did Macron win it on the backs of Paris? If France minus Paris went for Le Pen (or at least split) then the urban-rural split is enormous still.
Since we started separating out the popular vote from the Electoral vote in 1824 no candidate has ever received greater than 61% of the popular vote:
Franklin Roosevelt in 1936, Lyndon Johnson in 1964 and Richard Nixon in 1972. Warren G. Harding received 60% in 1920.