It is very difficult to disable runways and easy to repair them. You have to crater a lot of the concrete. There are special munitions for trying to do this such as the JP233. But these must be delivered at low-level. Very dangerous for the attacking aircraft.
In the first Gulf War, the RAF lost four Tornados trying to disable runways with JP233’s and had to change tactics and drop bombs from medium altitude using many sorties.
We have Tomahawks with cluster munitions to do that too, but it’s only an initial strike to establish air-superiority, as someone else here noted.