Wouldn’t take impeachment with Trump. If he goes too far Pence could say Trump went nuts and invoke the 25th to take over and the Rats & Rinos in Congress would join to make it so. Fat chance they’d do the same to Hillary. Unlike Clintons, past and future, and Obama, Trump will face checks and balances.
That’s absurd, no one is going to rely on the “inabilities” clause of the 25th Amendment in that context. Impeachment would be needed.