“It doesn’t take a mental heavy weight to recognize self inflicted idiocy.”
Or to dismiss empirical data from the Salk Institute because your good time comes out of a bottle.
Your supposition is that everyone relies on “substances” for a good time. It will most likely come as a great surprise or a complete disbelief to you that some people derive the same pleasures and even greater “highs” on sunsets, birds singing, and any number of other blessings free for the taking by everyone, no “substances” required. Poor you if you aren’t so blessed.