No relation. That was her married name. She was born in New York in 1862 and wrote novels of manners. Juseph Wharton, founder of Wharton School at University of Pennsylvania (located in Philadelphia), was an industrialist, born in Philadelphia in 1826, and made a donation to establish the school in 1881 in recognition that business was not taught as a discipline up until that time. He saw it as a way to help the burgeoning Industrial Revolution.
For the benefit of others who may be reading, University of Pennsylvania was founded in Philadelphia in 1740 by Benjamin Franklin -- before the U.S. Revolution, and is one of the Ivy League. It is nicknamed UPenn or simply "Penn."
Many confuse UPenn with Penn State, but the two universites are not connected. Penn State was founded more than 100 years later (1855) and is smack in the middle of the very wide state of Pennsylvania (Philadelphia being in the farthest eastern part of the state).
I knew there was no connection. Just pretending to be woo-woo.
Should be Joseph Wharton. Pardon the typo!